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3565776 ced-9

3565776

ced-9

Apoptosis regulator ced-9

protein-coding

Caenorhabditis elegans

基因描述

Type Description
Definition Apoptosis regulator ced-9

研究结论

Date Results Publications
2017-05-27 11:16:00 A protein interaction cascade involving EGL-1, CED-9, CED-4, and CED-3 results in the activation of the key cell death protease CED-3, which is tightly controlled by multiple positive and negative regulators. 27516615
2014-08-09 11:02:00 CED-9/Bcl-2 downregulation via LIN-35/Rb triggers germ cell apoptosis in C. elegans in response to starvation. 24752899
2013-01-26 11:17:00 HBx interacts directly with the B-cell lymphoma 2 (Bcl-2) homolog CED-9 (cell death abnormal) through a Bcl-2 homology 3 (BH3)-like motif to trigger both cytosolic Ca(2+) increase and cell death. 23091037
2012-06-09 10:54:00 CED-9 associates with the outer mitochondrial membrane within distinct foci that do not overlap with CED-4 21886181
2011-12-17 11:40:00 propose that EGL-1 converts CED-9 into a mitochondrial receptor for DRP-1, thereby shifting its activity from profusion to profission. 21949250

名称对应

Type IDs
Gene
UniProtKB-ID: CED9_CAEEL
UniprotKB: P41958
UniParc: UPI00001274CA
EMBL: L26545, Z29443
EnsemblGenome: WBGene00000423
KO: cel:CELE_T07C4.8
Nucleutide sequences
EMBL-CDS: AAA20080.1, CAA82573.2
Gene_ORFName: T07C4.8
EnsemblGenome_TRS: T07C4.8.1
Protein sequencees
EnsemblGenome_PRO: T07C4.8.1
RefSeq: NP_499284.1
Others
UniRef100: UniRef100_P41958
UniRef90: UniRef90_P41958
UniRef50: UniRef50_P41958
UniGene: Cel.6305

全选

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