| Type | Description |
|---|---|
| Definition | costa |
| Date | Results | Publications |
|---|---|---|
| 2019-03-23 12:03:00 | Evolutionarily selected sequence differences enable immotile Cos2 motors to function not as transporters but as microtubule-based tethers of signaling complexes. | 29351996 |
| 2018-10-27 12:03:00 | Cos2 is sumoylated, which counteracts its inhibitory role on Smo accumulation in the wing. | 28195188 |
| 2017-04-29 12:14:00 | We identified Ubr3, an E3 ubiquitin ligase, as a novel, positive regulator of Hh signaling in Drosophila and vertebrates. Hh signaling regulates the Ubr3-mediated poly-ubiquitination and degradation of Cos2, a central component of Hh signaling. In developing Drosophila eye discs, loss of ubr3 leads to a delayed differentiation of photoreceptors and a reduction in Hh signaling. | 27195754 |
| 2016-05-14 11:08:00 | Data show Ci interaction with Su(fu) or Cos2 correlates with Su(fu)- or Cos2-mediated suppression of Ci activity | 26271100 |
| 2015-04-25 12:26:00 | Data show that normal Ci-155 activation by Hh requires Cos2 binding to Fu, supporting the hypothesis that Cos2 mediates the apposition of Fu molecules suitable for cross-phosphorylation and consequent full activation of Fu kinase. | 25633354 |
| Type | IDs |
|---|---|
| Synonymous | CG1708, COS2, COS[2], Cos, Cos-2, Cos2, Cos[2], DmCos2, Dmel\CG1708, KIF26A/B, Kif7, cos-2, cos2, l(2)161/28, l(2)cos[[2]], l(2)k16101, l(2)k16128 |
| Gene |
UniProtKB-ID:
COS_DROME,
A0A0B4KED9_DROME
UniprotKB:
O16844,
A0A0B4KED9
UniParc:
UPI000007D300
EMBL:
BT001504,
AF019250,
BT015259,
AE013599,
BT044167
EnsemblGenome:
FBgn0000352
KO:
dme:Dmel_CG1708
|
| Nucleutide sequences |
EMBL-CDS:
AAF59270.1,
AAT94488.1,
ACH92232.1,
AAN71259.1,
AAB66813.1,
AGB93298.1
Gene_ORFName:
CG1708,
Dmel_CG1708,
CG1708
EnsemblGenome_TRS:
FBtr0089015,
FBtr0336916,
FBtr0336916,
FBtr0089015
|
| Protein sequencees |
EnsemblGenome_PRO:
FBpp0088087,
FBpp0307854,
FBpp0307854,
FBpp0088087
RefSeq:
NP_001260765.1,
NP_477092.1
|
| Others |
UniRef100:
UniRef100_O16844
UniRef90:
UniRef90_O16844
UniRef50:
UniRef50_O16844
UniGene:
Dm.5775
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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