Dscam1 - Down syndrome cell adhesion molecule 1-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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35652 Dscam1

基因描述

Type	Description
Definition	Down syndrome cell adhesion molecule 1

研究结论

Date	Results	Publications
2020-09-12 16:03:00	Dscam1 establishes the columnar units through lineage-dependent repulsion between sister neurons in the fly brain.	32792493
2020-08-01 10:10:00	The Dscam1 long was found to be required for correct Elav-mediated skipping of exon 19. Elav thus co-regulates APA and alternative splicing to generate specific Dscam1 transcripts that are essential for neural development.	31242415
2020-02-22 13:00:00	Accumulating evidence has shown that RNA structures play a crucial role in the regulation of alternative splicing of four exon clusters of Dscam1. [review]	31048027
2020-01-11 12:10:00	data argue for a small complement of regulatory factors as main determinants of exon inclusion in the Dscam exon 9 cluster	31292260
2019-09-07 11:15:00	This work identifies DSCAM as a candidate causative gene in Down syndrome that is sufficient to modify synaptic transmission and synaptic plasticity and cause a Down syndrome behavioural phenotype	29196216

名称对应

Type	IDs
Synonymous	43Bc, CG17800, CT39257, DSCAM, DScam, DmDscam, Dm_2R:13579, Dm_2R:13612, Dmel\CG17800, DsCam, Dscam, Dscam-hv, Dsm, FBgn0033159, Neu1, dScam, dscam, dscam1, l(2)05518, l(2)43Bc, p270
Gene	UniProtKB-ID: A0A0B4K6Z3_DROME, Q0E9I4_DROME, Q0E9J9_DROME, A1Z6X2_DROME, A0A0B4K7I5_DROME, Q0E9L6_DROME, Q0E9K1_DROME, Q0E9K6_DROME, Q0E9I8_DROME, Q0E9H6_DROME, A0A0B4K7T6_DROME, Q0E9I2_DROME, Q0E9L4_DROME, Q0E9M2_DROME, A0A0B4K6Z6_DROME, Q0E9K3_DROME, A0A0B4K824_DROME, Q0E9L1_DROME, A0A0C4DHD8_DROME, A0A0B4KEF4_DROME, Q0E9L5_DROME, A0A0B4K823_DROME, Q0E9K9_DROME, A0A0B4K7I3_DROME, A0A0B4K6S2_DROME, A0A0B4K6Y9_DROME, Q0E9L8_DROME, Q0E9I3_DROME, A1Z6X3_DROME, A0A0B4K7T5_DROME, A0A0B4K6R8_DROME, Q0E9K8_DROME, A0A0B4K827_DROME, Q0E9M0_DROME, Q0E9L3_DROME, A0A0B4K7H9_DROME, Q0E9I0_DROME, Q0E9J6_DROME, Q0E9J1_DROME, Q0E9J4_DROME, Q0E9K4_DROME, Q0E9H5_DROME, Q0E9J8_DROME, Q0E9I6_DROME, A0A0B4K6Z8_DROME, Q0E9J5_DROME, A0A0B4K7T8_DROME, A0A0B4K7H7_DROME, Q0E9I9_DROME, A0A0B4K6Q9_DROME, Q0E9J3_DROME, A1Z6X1_DROME, Q0E9I5_DROME, Q0E9M3_DROME, Q0E9L7_DROME, Q0E9K0_DROME, Q0E9I1_DROME, Q0E9K5_DROME, Q0E9L2_DROME, Q0E9H7_DROME, Q0E9I7_DROME, Q0E9L0_DROME, Q0E9J0_DROME, Q0E9J2_DROME, A0A0B4K828_DROME, Q0E9K2_DROME, Q0E9K7_DROME, Q0E9M1_DROME, Q0E9M4_DROME, Q0E9H8_DROME, A0A0B4K6R4_DROME, Q0E9H9_DROME, Q0E9J7_DROME, A0A0B4K7T4_DROME, Q0E9L9_DROME UniprotKB: A0A0B4K6Z3, Q0E9I4, Q0E9J9, A1Z6X2, A0A0B4K7I5, Q0E9L6, Q0E9K1, Q0E9K6, Q0E9I8, Q0E9H6, A0A0B4K7T6, Q0E9I2, Q0E9L4, Q0E9M2, A0A0B4K6Z6, Q0E9K3, A0A0B4K824, Q0E9L1, A0A0C4DHD8, A0A0B4KEF4, Q0E9L5, A0A0B4K823, Q0E9K9, A0A0B4K7I3, A0A0B4K6S2, A0A0B4K6Y9, Q0E9L8, Q0E9I3, A1Z6X3, A0A0B4K7T5, A0A0B4K6R8, Q0E9K8, A0A0B4K827, Q0E9M0, Q0E9L3, A0A0B4K7H9, Q0E9I0, Q0E9J6, Q0E9J1, Q0E9J4, Q0E9K4, Q0E9H5, Q0E9J8, Q0E9I6, A0A0B4K6Z8, Q0E9J5, A0A0B4K7T8, A0A0B4K7H7, Q0E9I9, A0A0B4K6Q9, Q0E9J3, A1Z6X1, Q0E9I5, Q0E9M3, Q0E9L7, Q0E9K0, Q0E9I1, Q0E9K5, Q0E9L2, Q0E9H7, Q0E9I7, Q0E9L0, Q0E9J0, Q0E9J2, A0A0B4K828, Q0E9K2, Q0E9K7, Q0E9M1, Q0E9M4, Q0E9H8, A0A0B4K6R4, Q0E9H9, Q0E9J7, A0A0B4K7T4, Q0E9L9 UniParc: UPI0000DF03AC, UPI0000DF03B6, UPI000237F48A, UPI000237F48C, UPI0000DF03A6, UPI000237F47C, UPI000237F480, UPI0000DF03A7, UPI0000DF03B1, UPI000237F4A6, UPI0000DF03A9, UPI0000DF03A1, UPI000237F494, UPI0000DF03CF, UPI000237F48F, UPI0000DF03A5, UPI0000DF03AA, UPI0000DF03C6, UPI000237F498, UPI000237F489, UPI0000DF03C5, UPI0000DF03B8, UPI0000DF03B9, UPI000237F47B, UPI0000DF03BB, UPI0000DF03CD, UPI0000DF03A0, UPI000237F481, UPI000034E0A2, UPI0000DF03B7, UPI0000DF03CE, UPI000237F49C, UPI0000DF03C4, UPI0000DF03BE, UPI0000DF03C9, UPI0000DF03B0, UPI0000DF03D0, UPI0000DF03C0, UPI0000DF03A4, UPI0000DF03BF, UPI0000DF03B4, UPI0000DF03B3, UPI0000DF03A2, UPI0000DF03A8, UPI0000DF03CA, UPI0002ADBDDC, UPI0000DF03BC, UPI0000DF03C2, UPI000237F4A1, UPI0000DF03CB, UPI0000DF03AD, UPI0000DF03BD, UPI0000DF03B5, UPI0000DF03A3, UPI0000DF03AE, UPI0000DF03AB, UPI00000798DE, UPI000007887D, UPI000237F493, UPI0000DF03BA, UPI0000DF03C7, UPI000237F49B, UPI0000DF03C3, UPI000237F4A0, UPI000237F492, UPI0000DF03CC, UPI000237F48E, UPI0000DF03B2, UPI0000DF03C1, UPI00000798C0, UPI0000DF03C8, UPI000237F4A4, UPI0000DF03AF, UPI000237F4A3, UPI000237F49A EMBL: AE013599 EnsemblGenome: FBgn0033159 KO: dme:Dmel_CG17800
Nucleutide sequences	EMBL-CDS: AFH07926.1, ABI31049.1, ABI31069.1, AAS64901.1, AFH07933.1, ABI31055.1, ABI31029.1, ABI31030.1, ABI31072.1, ABI31076.1, AFH07929.1, ABI31071.1, ABI31037.1, ABI31050.1, AFH07931.1, ABI31056.1, AFH07922.1, ABI31039.1, AAM68885.2, AGB93297.1, ABI31053.1, AFH07917.1, ABI31075.1, AFH07928.1, AFH07935.1, AFH07921.1, ABI31031.1, ABI31060.1, AAM68884.1, AFH07924.1, AFH07930.1, ABI31054.1, AFH07927.1, ABI31040.1, ABI31035.1, AFH07923.1, ABI31038.1, ABI31077.1, ABI31068.1, ABI31066.1, ABI31057.1, ABI31065.1, ABI31078.1, ABI31051.1, AFH07936.1, ABI31028.1, AFH07934.1, AFH07918.1, ABI31046.1, AFH07920.1, ABI31052.1, AAM68883.1, ABI31044.1, ABI31036.1, ABI31033.1, ABI31064.1, ABI31074.1, ABI31061.1, ABI31043.1, ABI31063.1, ABI31034.1, ABI31067.1, ABI31042.1, ABI31032.1, AFH07932.1, ABI31079.1, ABI31073.1, ABI31041.1, ABI31027.1, ABI31045.1, AFH07925.1, AAF59271.2, ABI31080.1, AFH07919.1, ABI31048.1 Gene_ORFName: CG17800, Dmel_CG17800, Dmel_CG17800, CG17800, Dmel_CG17800, CG17800, CG17800, Dmel_CG17800, Dmel_CG17800, CG17800, Dmel_CG17800, CG17800, Dmel_CG17800, CG17800, Dmel_CG17800, CG17800, Dmel_CG17800, CG17800, Dmel_CG17800, CG17800, Dmel_CG17800, CG17800, Dmel_CG17800, CG17800, CG17800, Dmel_CG17800, CG17800, Dmel_CG17800, CG17800, Dmel_CG17800, CG17800, Dmel_CG17800, CG17800, Dmel_CG17800, Dmel_CG17800, CG17800, CG17800, Dmel_CG17800, Dmel_CG17800, CG17800, Dmel_CG17800, CG17800, Dmel_CG17800, CG17800, Dmel_CG17800, CG17800, CG17800, Dmel_CG17800, Dmel_CG17800, CG17800, CG17800, Dmel_CG17800, Dmel_CG17800, CG17800, Dmel_CG17800, CG17800, Dmel_CG17800, CG17800, Dmel_CG17800, CG17800, Dmel_CG17800, CG17800, Dmel_CG17800, CG17800, CG17800, Dmel_CG17800, Dmel_CG17800, CG17800, Dmel_CG17800, CG17800, Dmel_CG17800, CG17800, CG17800, Dmel_CG17800, Dmel_CG17800, CG17800, CG17800, Dmel_CG17800, CG17800, Dmel_CG17800, Dmel_CG17800, CG17800, CG17800, Dmel_CG17800, Dmel_CG17800, CG17800, Dmel_CG17800, CG17800, Dmel_CG17800, CG17800, Dmel_CG17800, CG17800, Dmel_CG17800, CG17800, CG17800, Dmel_CG17800, Dmel_CG17800, CG17800, CG17800, Dmel_CG17800, CG17800, Dmel_CG17800, CG17800, Dmel_CG17800, Dmel_CG17800, CG17800, Dmel_CG17800, CG17800, Dmel_CG17800, CG17800, CG17800, Dmel_CG17800, Dmel_CG17800, CG17800, CG17800, Dmel_CG17800, Dmel_CG17800, CG17800, CG17800, Dmel_CG17800, Dmel_CG17800, CG17800, Dmel_CG17800, CG17800, Dmel_CG17800, CG17800, CG17800, Dmel_CG17800, Dmel_CG17800, CG17800, CG17800, Dmel_CG17800, CG17800, Dmel_CG17800, CG17800, Dmel_CG17800, CG17800, Dmel_CG17800, Dmel_CG17800, CG17800, Dmel_CG17800, CG17800, Dmel_CG17800, CG17800, CG17800, Dmel_CG17800, Dmel_CG17800, CG17800, CG17800, Dmel_CG17800 EnsemblGenome_TRS: FBtr0306776, FBtr0111089, FBtr0111055, FBtr0089020, FBtr0306784, FBtr0111068, FBtr0111076, FBtr0111060, FBtr0111097, FBtr0111082, FBtr0306779, FBtr0111087, FBtr0111066, FBtr0111073, FBtr0306781, FBtr0111058, FBtr0306772, FBtr0111064, FBtr0306783, FBtr0334801, FBtr0111067, FBtr0306767, FBtr0111062, FBtr0306778, FBtr0306786, FBtr0306771, FBtr0111070, FBtr0111088, FBtr0089018, FBtr0306774, FBtr0306780, FBtr0111102, FBtr0306777, FBtr0111075, FBtr0111065, FBtr0306773, FBtr0111084, FBtr0111052, FBtr0111100, FBtr0111050, FBtr0111077, FBtr0111081, FBtr0111054, FBtr0111094, FBtr0306787, FBtr0111051, FBtr0306785, FBtr0306768, FBtr0111098, FBtr0306770, FBtr0111049, FBtr0089019, FBtr0111092, FBtr0111074, FBtr0111069, FBtr0111056, FBtr0111085, FBtr0111059, FBtr0111101, FBtr0111083, FBtr0111096, FBtr0111063, FBtr0111099, FBtr0111079, FBtr0306782, FBtr0111057, FBtr0111061, FBtr0111072, FBtr0111080, FBtr0111078, FBtr0306775, FBtr0089016, FBtr0111053, FBtr0306769, FBtr0111071
Protein sequencees	EnsemblGenome_PRO: FBpp0297692, FBpp0110384, FBpp0110347, FBpp0089327, FBpp0297700, FBpp0110362, FBpp0110370, FBpp0110352, FBpp0110392, FBpp0110376, FBpp0297695, FBpp0110381, FBpp0110360, FBpp0110367, FBpp0297697, FBpp0110350, FBpp0297688, FBpp0110357, FBpp0297699, FBpp0306847, FBpp0110361, FBpp0297683, FBpp0110355, FBpp0297694, FBpp0297702, FBpp0297687, FBpp0110364, FBpp0110382, FBpp0088090, FBpp0297690, FBpp0297696, FBpp0110354, FBpp0297693, FBpp0110369, FBpp0110359, FBpp0297689, FBpp0110378, FBpp0110344, FBpp0110395, FBpp0110342, FBpp0110371, FBpp0110375, FBpp0110346, FBpp0110389, FBpp0297703, FBpp0110343, FBpp0297701, FBpp0297684, FBpp0110393, FBpp0297686, FBpp0110341, FBpp0088091, FBpp0110387, FBpp0110368, FBpp0110363, FBpp0110348, FBpp0110379, FBpp0110351, FBpp0110358, FBpp0110377, FBpp0110391, FBpp0110356, FBpp0110394, FBpp0110373, FBpp0297698, FBpp0110349, FBpp0110353, FBpp0110366, FBpp0110374, FBpp0110372, FBpp0297691, FBpp0088088, FBpp0110345, FBpp0297685, FBpp0110365 RefSeq: NP_001036481.1, NP_001036525.1, NP_001036523.1, NP_001036506.1, NP_001036480.1, NP_001036501.1, NP_001246164.1, NP_001036494.1, NP_001036502.1, NP_001036522.1, NP_001246162.1, NP_001036524.1, NP_001036498.1, NP_724543.1, NP_001036515.1, NP_001036499.1, NP_001036510.1, NP_001036518.1, NP_001036476.1, NP_001246180.1, NP_001036520.1, NP_724542.1, NP_724544.2, NP_001036517.1, NP_001246179.1, NP_001036521.1, NP_001036516.1, NP_001260764.1, NP_001246168.1, NP_001036509.1, NP_001036490.1, NP_001246166.1, NP_001036484.1, NP_001246172.1, NP_001036495.1, NP_001036483.1, NP_001246167.1, NP_001036479.1, NP_001036477.1, NP_001246170.1, NP_001246175.1, NP_001246171.1, NP_001036491.1, NP_001036513.1, NP_001246165.1, NP_001246176.1, NP_995769.1, NP_001036493.1, NP_001036478.1, NP_001036529.1, NP_523649.5, NP_001246173.1, NP_001036486.1, NP_001246174.1, NP_001036485.1, NP_001246178.1, NP_001036503.1, NP_001036526.1, NP_001036482.1, NP_001246169.1, NP_001036497.1, NP_001036492.1, NP_001036528.1, NP_001036504.1, NP_001036505.1, NP_001036512.1, NP_001246181.1, NP_001036527.1, NP_001036500.1, NP_001036489.1, NP_001036487.1, NP_001246177.1, NP_001036514.1, NP_001036488.1, NP_001246163.1
Others	UniRef100: UniRef100_Q0E9J1, UniRef100_Q0E9I8, UniRef100_A0A0B4K6S2, UniRef100_Q0E9J5, UniRef100_Q0E9J2, UniRef100_Q0E9K2, UniRef100_A0A0B4K7H7, UniRef100_A0A0B4K6Z6, UniRef100_A1Z6X3, UniRef100_Q0E9H6, UniRef100_A1Z6X2, UniRef100_A0A0C4DHD8, UniRef100_Q0E9J4, UniRef100_Q0E9I9, UniRef100_Q0E9J7, UniRef100_Q0E9L0, UniRef100_A0A0B4K7I5, UniRef100_Q0E9J0, UniRef100_Q0E9H9, UniRef100_A0A0B4K7T6, UniRef100_Q0E9M3, UniRef100_Q0E9L8, UniRef100_Q0E9J3, UniRef100_Q0E9K3, UniRef100_Q0E9L3, UniRef100_A0A0B4K824, UniRef100_Q0E9I6, UniRef100_Q0E9H5, UniRef100_Q0E9I2, UniRef100_A0A0B4K7H9, UniRef100_Q0E9J9, UniRef100_Q0E9L2, UniRef100_Q0E9M0, UniRef100_A0A0B4K6R8, UniRef100_Q0E9I0, UniRef100_Q0E9J6, UniRef100_A0A0B4K827, UniRef100_A0A0B4K7T4, UniRef100_A0A0B4KEF4, UniRef100_Q0E9L4, UniRef100_Q0E9I7, UniRef100_A0A0B4K7I3, UniRef100_A0A0B4K6R4, UniRef100_Q0E9K9, UniRef100_Q0E9J8, UniRef100_Q0E9I5, UniRef100_A0A0B4K6Q9, UniRef100_Q0E9M4, UniRef100_A1Z6X1, UniRef100_Q0E9I3, UniRef100_Q0E9L7, UniRef100_Q0E9L1, UniRef100_Q0E9K1, UniRef100_Q0E9L5, UniRef100_A0A0B4K7T8, UniRef100_A0A0B4K7T5, UniRef100_A0A0B4K6Z3, UniRef100_Q0E9M2, UniRef100_Q0E9K0, UniRef100_Q0E9I4, UniRef100_Q0E9K5, UniRef100_Q0E9K4, UniRef100_Q0E9H7, UniRef100_Q0E9L9, UniRef100_A0A0B4K6Z8, UniRef100_Q0E9K8, UniRef100_Q0E9M1, UniRef100_Q0E9K6, UniRef100_Q0E9K7, UniRef100_A0A0B4K823, UniRef100_Q0E9I1, UniRef100_Q0E9L6, UniRef100_Q0E9H8, UniRef100_A0A0B4K6Y9, UniRef100_A0A0B4K828 UniRef90: UniRef90_A0A0B4K6Z6, UniRef90_A0A0B4K7T8, UniRef90_Q0E9J2, UniRef90_Q0E9K1, UniRef90_A0A0B4K7I3, UniRef90_Q0E9H6, UniRef90_A1Z6X2, UniRef90_A0A0B4K6R4, UniRef90_A0A0B4K6Z8, UniRef90_A0A0B4K824, UniRef90_Q0E9M2, UniRef90_Q0E9J4, UniRef90_A0A0B4K6S2, UniRef90_Q0E9J0, UniRef90_Q0E9L5, UniRef90_Q0E9I2, UniRef90_Q0E9H8, UniRef90_Q0E9K9, UniRef90_Q0E9I4, UniRef90_Q0E9L0, UniRef90_A0A0B4K823, UniRef90_A1Z6X1, UniRef90_A0A0B4K6Z3, UniRef90_Q0E9K7, UniRef90_Q0E9L2, UniRef90_Q0E9M1, UniRef90_Q0E9I5, UniRef90_A1Z6X3, UniRef90_A0A0B4K827, UniRef90_Q0E9H9, UniRef90_Q0E9J9, UniRef90_A0A0C4DHD8, UniRef90_Q0E9K4, UniRef90_A0A0B4K6Y9, UniRef90_Q0E9L3, UniRef90_Q0E9K3, UniRef90_Q0E9I3, UniRef90_Q0E9L7, UniRef90_Q0E9K0, UniRef90_A0A0B4K7T5, UniRef90_Q0E9M4, UniRef90_Q0E9K8, UniRef90_A0A0B4KEF4, UniRef90_Q0E9H7, UniRef90_Q0E9L6, UniRef90_Q0E9I8, UniRef90_Q0E9J5, UniRef90_Q0E9H5, UniRef90_A0A0B4K7H9, UniRef90_A0A0B4K7I5, UniRef90_Q0E9M0 UniRef50: UniRef50_A0A0B4K6Z6, UniRef50_Q0E9K7, UniRef50_A0A0B4KEF4, UniRef50_Q0E9L5 UniGene: Dm.2832

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mRNA

Protein

UniprotKB

Description

Refseq

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Pubmed编号	文献信息	发表日期	相关基因
32792493	Dscam1 establishes the columnar units through lineage-dependent repulsion between sister neurons in the fly brain. Nat Commun Chuyan Liu , Olena Trush , Xujun Han , Miaoxing Wang , Rie Takayama , Tetsuo Yasugi , Takashi Hayashi , Makoto Sato	2020-08-13	-
31430488	Pattern recognition receptors in Drosophila immune responses. Dev. Comp. Immunol. Yuzhen Lu , Fanghua Su , Qilin Li , Jie Zhang , Yanjun Li , Ting Tang , Qihao Hu , Xiao-Qiang Yu	2020-01-01	-
31292260	Srrm234, but not canonical SR and hnRNP proteins, drive inclusion of Dscam exon 9 variable exons. RNA Pinar Ustaoglu , Irmgard U Haussmann , Hongzhi Liao , Antonio Torres-Mendez , Roland Arnold , Manuel Irimia , Matthias Soller	2019-10-01	-
31399611	Inter-axonal recognition organizes Drosophila olfactory map formation. Sci Rep Gaurav Goyal , Ariane Zierau , Marc Lattemann , Beate Bergkirchner , Dominik Javorski , Rashmit Kaur , Thomas Hummel	2019-08-09	-
31242415	Elav-Mediated Exon Skipping and Alternative Polyadenylation of the Dscam1 Gene Are Required for Axon Outgrowth. Cell Rep Zhiping Zhang , Kevin So , Ryan Peterson , Matthew Bauer , Henry Ng , Yong Zhang , Jung Hwan Kim , Thomas Kidd , Pedro Miura	2019-06-25	-
30953686	Phagocytosis in Drosophila: From molecules and cellular machinery to physiology. Insect Biochem. Mol. Biol. C Melcarne , B Lemaitre , E Kurant	2019-06-01	-
31138234	Drosophila Netrin-B controls mushroom body axon extension and regulates courtship-associated learning and memory of a Drosophila fragile X syndrome model. Mol Brain Huaixing Kang , Juan Zhao , Xuan Jiang , Guangxu Li , Wen Huang , Huili Cheng , Ranhui Duan	2019-05-28	-
31048027	Role of RNA secondary structures in regulating Dscam alternative splicing. Biochim Biophys Acta Gene Regul Mech Bingbing Xu , Yang Shi , Yandan Wu , Yijun Meng , Yongfeng Jin	2019-04-29	-
30992041	Studying alcohol use disorder using Drosophila melanogaster in the era of 'Big Data'. Behav Brain Funct Gregory L Engel , Kreager Taber , Elizabeth Vinton , Amanda J Crocker	2019-04-16	-
30541104	Plasmid-based gap-repair recombineered transgenes reveal a central role for introns in mutually exclusive alternative splicing in Down Syndrome Cell Adhesion Molecule exon 4. Nucleic Acids Res. Irmgard U Haussmann , Pinar Ustaoglu , Ulrike Brauer , Yash Hemani , Thomas C Dix , Matthias Soller	2019-02-20	-

研究热度

热点单位

排名	科研单位	文献
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目前还没有研究热点单位

热点人员

排名	研究人员	文献
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目前还没有研究热点人员

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