| Type | Description |
|---|---|
| Definition | maleless |
| Date | Results | Publications |
|---|---|---|
| 2020-05-16 11:14:00 | ENY2 Protein Interacts with RNA Helicase MLE | 32130612 |
| 2019-11-30 11:19:00 | Structure, dynamics and roX2-lncRNA binding of tandem double-stranded RNA binding domains dsRBD1,2 of Drosophila helicase Maleless has been reported. | 30805612 |
| 2019-10-12 11:41:00 | our research provides structural insights into the interactions between MLE dsRBDs and R2H1 and facilitates a deeper understanding of the mechanism by which MLE tandem dsRBDs play an indispensable role in specific recognition of roX and the assembly of the MSL-DCC in Drosophila dosage compensation. | 30649456 |
| 2017-07-01 10:23:00 | We have employed a systems biology approach (microarray) to investigate the global aneuploid effect of the maleless (mle) mutation that disrupts the binding of male specific lethal (MSL) proteins that function in dosage compensation. | 27456781 |
| 2016-05-14 11:49:00 | MLE specifically targets hairpin RNAs at their site of transcription. The association of MLE at these sites is independent of sequence and chromosome location | 26752049 |
| Type | IDs |
|---|---|
| Synonymous | CG11680, Dmel\CG11680, MLE, Mle, dDHX9, mak, mll, mls, nap, nap[ts] |
| Gene |
UniProtKB-ID:
MLE_DROME
UniprotKB:
P24785
UniParc:
UPI000002AE21,
UPI000007C0CB,
UPI000000C163
EMBL:
M74121,
AE013599,
BT003785,
BT010267
EnsemblGenome:
FBgn0002774
KO:
dme:Dmel_CG11680
|
| Nucleutide sequences |
EMBL-CDS:
AAO41468.1,
AAQ23585.1,
AAF57297.1,
AAM68335.1,
AAC41573.1
Gene_ORFName:
CG11680
EnsemblGenome_TRS:
FBtr0100576,
FBtr0086031
|
| Protein sequencees |
EnsemblGenome_PRO:
FBpp0085367,
FBpp0100031
RefSeq:
NP_476641.1,
NP_724440.1
|
| Others |
UniRef100:
UniRef100_P24785
UniRef90:
UniRef90_P24785
UniRef50:
UniRef50_P24785
UniGene:
Dm.2901
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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