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35522 BubR1

35522

BubR1

Bub1-related kinase

protein-coding

Drosophila melanogaster

基因描述

Type Description
Definition Bub1-related kinase

研究结论

Date Results Publications
2020-09-12 14:52:00 The authors showed that BubR1-mediated the centromere-associated kinesin motor CENP-E phosphorylation produces a temporal switch that enables transition from lateral to end-on microtubule capture and organization of microtubules into stable midzone arrays. 31201382
2016-02-13 11:03:00 The Bub3-BubR1 complex on broken DNA inhibits the APC/C locally via the sequestration of Cdc20. 26553926
2013-08-31 12:36:00 a model in which Polo controls Mps1-dependent BubR1 phosphorylation to promote Cdc20 kinetochore recruitment and sustained SAC function. 23685359
2010-07-26 11:03:00 Data show that the Mad2 kinetochore dimerization recruitment mechanism is conserved and that the recruitment of Cdc20 to kinetochores in Drosophila requires BubR1 but not Mad2. 20421417
2010-03-01 11:13:00 Reduced BubR1 or Polo function results in abnormal segregation of acentric chromatids, a decrease in acentric chromosome tethering, and a great reduction in adult survival. 20141837

名称对应

Type IDs
Synonymous 31/13, BUB1, BUBR1, BcDNA:LD23835, Bub1, CG 7838, CG7838, DmBUB1, DmBubRI, Dmbub1, Dmel\CG7838, bub1, bubR1, bubr1, dBUB1, l(2)k03113, l(2)k06109, mcl(2)Z1525
Gene
UniProtKB-ID: A1Z6I7_DROME
UniprotKB: A1Z6I7
UniParc: UPI000007F8C4
EMBL: AE013599
EnsemblGenome: FBgn0263855
KO: dme:Dmel_CG7838
Nucleutide sequences
EMBL-CDS: AAF57298.1
Gene_ORFName: CG7838, Dmel_CG7838
EnsemblGenome_TRS: FBtr0086032
Protein sequencees
EnsemblGenome_PRO: FBpp0085368
RefSeq: NP_477382.1
Others
UniRef100: UniRef100_A1Z6I7
UniRef90: UniRef90_A1Z6I7
UniRef50: UniRef50_A1Z6I7
UniGene: Dm.6411

全选

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研究热度

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