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3550 IK

3550

IK

IK cytokine

protein-coding

Homo sapiens

基因描述

Type Description
Definition IK cytokine

研究结论

Date Results Publications
2020-04-11 12:45:00 Investigated and identified antiviral agents targeting the assembly of the human RED-SMU1 splicing complex, and results demonstrate possibility of RED-SMU1 destabilizing molecules to be used in antiviral therapy. 31076555
2020-01-11 10:03:00 Smu1 and RED function both as alternative splicing regulators and as general splicing factors and are required predominantly for efficient splicing of short introns. 31409787
2017-08-26 12:16:00 IK inhibits Aurora B activation through recruiting PP2A into IK and Aurora B complex. 26906715
2016-04-16 11:57:00 Data suggest an indirect radiosensitivity of hIK channels to low-dose photon irradiation with an impact on cell differentiation. 25277267
2015-08-15 11:27:00 Data suggest that two human spliceosomal factors, RED and SMU1, are recruited to control expression and alternative splicing of viral exportins via PB2 (polymerase PB2) of influenza A virus (H3N2) and are required for efficient viral multiplication. 24945353

名称对应

Type IDs
Synonymous CSA2, RED, RER
Gene
UniProtKB-ID: RED_HUMAN, Q95HA6_HUMAN, Q9UK43_HUMAN
UniprotKB: Q13123, Q95HA6, Q9UK43
UniParc: UPI000008AF01, UPI000006F3A3, UPI0000378337
EMBL: BC013005, AJ005579, BC071964, S74221, AC116353, AF182645
Ensembl: ENSG00000113141
KO: hsa:3550
Nucleutide sequences
EMBL-CDS: CAA06607.1, AAH71964.1, AAB32531.1, AAH13005.1, AAD55447.1
Ensembl_TRS: ENST00000417647
Protein sequencees
Ensembl_PRO: ENSP00000396301
RefSeq: NP_006074.2
Others
UniRef100: UniRef100_Q9UK43, UniRef100_Q13123, UniRef100_Q95HA6
UniRef90: UniRef90_Q13123
UniRef50: UniRef50_Q13123
UniGene: Hs.421245
CCDS: CCDS47280.1

全选

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研究热度

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