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35445 Clamp

35445

Clamp

Chromatin-linked adaptor for MSL proteins

protein-coding

Drosophila melanogaster

基因描述

Type Description
Definition Chromatin-linked adaptor for MSL proteins

研究结论

Date Results Publications
2020-07-04 11:03:00 proper MSL2 positioning requires an interaction with either CLAMP or DNA to initiate dosage compensation in Drosophila males. 31320325
2019-08-24 10:39:00 hese are explained by physical interaction between MSL2 and CLAMP. In vivo, both factors cooperate to compete with nucleosome formation at HAS. The male-specific MSL2 thus synergises with a ubiquitous GA-repeat binding protein for refined X/autosome discrimination 30541149
2018-03-10 11:02:00 CLAMP regulates roX (RNA on the X) abundance in a sex-specific manner. 27995349
2018-02-03 11:07:00 demonstrate that CLAMP associates with the transcriptional regulator complex Negative Elongation Factor (NELF) in both sexes and determine that CLAMP reduces NELF recruitment to several target genes 29281702
2017-12-02 11:25:00 CLAMP increases chromatin accessibility, enhances histone gene transcription, and promotes histone locus body formation. 28838946

名称对应

Type IDs
Synonymous CG1832, CLAMP, Dmel\CG1832, clamp
Gene
UniProtKB-ID: Q8IGP5_DROME, Q9V9N4_DROME
UniprotKB: Q8IGP5, Q9V9N4
UniParc: UPI000008511B, UPI0000083CC1
EMBL: AE014134, BT001676, BT001891
EnsemblGenome: FBgn0032979
KO: dme:Dmel_CG1832
Nucleutide sequences
EMBL-CDS: AAN71431.1, AAX52677.1, AAN71680.1, AAF57252.1
Gene_ORFName: Dmel_CG1832, CG1832, Dmel_CG1832, CG1832
EnsemblGenome_TRS: FBtr0100407, FBtr0085964
Protein sequencees
EnsemblGenome_PRO: FBpp0099821, FBpp0085317
RefSeq: NP_001014498.1, NP_610137.1
Others
UniRef100: UniRef100_Q8IGP5, UniRef100_Q9V9N4
UniRef90: UniRef90_Q9V9N4, UniRef90_Q8IGP5
UniRef50: UniRef50_Q8IGP5
UniGene: Dm.7292

全选

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