| Type | Description |
|---|---|
| Definition | nuclear receptor subfamily 1, group D, member 2 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-06 13:31:00 | Dysregulation of REV-ERBalpha impairs GABAergic function and promotes epileptic seizures in preclinical models. | 33619249 |
| 2021-01-16 15:54:00 | Pharmacological modulation and genetic deletion of REV-ERBalpha and REV-ERBbeta regulates dendritic cell development. | 32439175 |
| 2020-11-21 13:21:00 | Inhibition of REV-ERBs stimulates microglial amyloid-beta clearance and reduces amyloid plaque deposition in the 5XFAD mouse model of Alzheimer's disease. | 31800167 |
| 2020-07-04 11:45:00 | this study showsev-erbalpha negatively regulated osteoclast and osteoblast differentiation by suppressing the p38 MAPK pathway | 31896234 |
| 2019-05-11 10:16:00 | Rev-erbalpha is a pharmacologically accessible link between the circadian clock and neuroinflammation. | 30792350 |
| Type | IDs |
|---|---|
| Synonymous | RVR, Rev-erb |
| Gene |
UniProtKB-ID:
NR1D2_MOUSE,
Q8C6J1_MOUSE,
Q8C598_MOUSE,
Q4VAB7_MOUSE
UniprotKB:
Q60674,
Q8C6J1,
Q8C598,
Q4VAB7
UniParc:
UPI00000E9B2B,
UPI000002820E,
UPI00000E9CC4
EMBL:
AK079075,
AK054522,
U09504,
U12142,
BC096461
Ensembl:
ENSMUSG00000021775
KO:
mmu:353187
|
| Nucleutide sequences |
EMBL-CDS:
AAC52144.1,
AAA79513.1,
BAC35811.1,
BAC37525.1,
AAH96461.1
Ensembl_TRS:
ENSMUST00000090543
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000088031
RefSeq:
XP_036014581.1,
XP_036014580.1,
NP_035714.3
|
| Others |
UniRef100:
UniRef100_Q8C598,
UniRef100_Q8C6J1,
UniRef100_Q60674
UniRef90:
UniRef90_Q60674,
UniRef90_Q63504-2
UniRef50:
UniRef50_Q60674,
UniRef50_Q63504-2
UniGene:
Mm.26587
CCDS:
CCDS36811.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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