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352930 gli1

352930

gli1

GLI family zinc finger 1

protein-coding

Danio rerio

基因描述

Type Description
Definition GLI family zinc finger 1

研究结论

Date Results Publications
2017-09-23 11:48:00 Mutation of hmgcs1 had no effect on Shh signaling at 2 and 3 days post fertilization (dpf), but did result in a decrease in the expression of gli1, a known Shh target gene, at 4 dpf, after morphological deficits in craniofacial development and chondrocyte differentiation were observed in hmgcs1 mutants. 28686747
2014-11-08 12:09:00 a new mechanism of Gli transcription factor activation and implicate ARHGAP36 dysregulation in the onset and/or progression of GLI-dependent cancers. 25024229
2014-08-23 10:13:00 We show that Kif7 interacts with both Gli1 and Gli2a and suggest that it functions to sequester Gli proteins in the cytoplasm, in a manner analogous to the regulation of Ci by Cos2 in Drosophila. 24339784
2012-01-07 11:34:00 Gli1 has a Hh-independent role in many motoneurons and V3 domain cells in embryos that lack Hh signalling, but removal of Gli1 activity does not affect more dorsal neurons. 22069186
2010-01-21 00:00:00 These results reveal divergent requirements for Gli1 and Gli2 in mouse and zebrafish and indicate that zebrafish Gli1 is an activator of Hh-regulated genes, while zebrafish Gli2 has minor roles as a repressor or activator of Hh targets. 12620981

名称对应

Type IDs
Gene
UniProtKB-ID: Q800Z9_DANRE
UniprotKB: Q800Z9
UniParc: UPI000005EFFF
EMBL: AY173030
KO: dre:352930
Nucleutide sequences
EMBL-CDS: AAO43495.1
Protein sequencees
RefSeq: NP_840081.2
Others
UniRef100: UniRef100_Q800Z9
UniRef90: UniRef90_F1QAC4
UniRef50: UniRef50_Q91690
UniGene: Dr.88778

全选

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