| Type | Description |
|---|---|
| Definition | loki |
| Date | Results | Publications |
|---|---|---|
| 2017-09-16 10:40:00 | this study demonstrates, that Lok kinase activation is required for the DNA damage-mediated disruption of adult stem cell self-renewal and lineage differentiation, and might also offer novel insight into how DNA damage causes tissue aging and cancer formation. | 27729408 |
| 2016-02-13 11:38:00 | FHA domain in Mnk plays dual functions in mediating embryonic DNA damage responses by means of its phosphopeptide-binding ability: activating Mnk in nucleus upon DNA damage &recruiting Mnk to multiple subcellular structures independently of DNA damage | 25808488 |
| 2014-12-20 12:00:00 | We conclude that the primary responsibility for maintaining genome integrity in the male germline lies with Chk2, and that P53 is required to reconstitute the germline when cells are eliminated owing to unrepaired DNA damage. | 24586185 |
| 2014-08-09 10:25:00 | nuclear retention involves Chk2-mediated inactivation of the Drosophila stem loop binding protein (SLBP), the levels of which are specifically depleted in damaged nuclei following Chk2 phosphorylation, an event that contributes to nuclear fallout. | 24835465 |
| 2013-08-03 11:35:00 | MOF controls Checkpoint protein2 and regulates genomic stability during early embryogenesis. | 23347679 |
| Type | IDs |
|---|---|
| Synonymous | 10895, 38B.4, CG10895, CHK-2, CHK2, Chk2, DmCHk2, DmChk2, Dmchk2, Dmel\CG10895, Dmnk, Dmnk-L, Dmnk-S, Dmnk/DChk2, LOKI/CHK2, Lok, MNK, chk, chk2, chk2/lok, mnk |
| Gene |
UniProtKB-ID:
LOK_DROME,
D3DMK7_DROME,
A4V0X0_DROME
UniprotKB:
O61267,
D3DMK7,
A4V0X0
UniParc:
UPI00001245C4,
UPI0001C30D9A,
UPI000002AD60
EMBL:
BT120173,
BT120181,
U87984,
AE014134,
AB007822,
AY070549,
AB007821
EnsemblGenome:
FBgn0019686
KO:
dme:Dmel_CG10895
|
| Nucleutide sequences |
EMBL-CDS:
AAN11062.1,
AAF53867.2,
AAL48020.1,
AAB49642.1,
BAA28756.1,
BAA28755.1,
AFH03774.1,
ADB91429.1,
ADB91421.1,
AAN11063.1
Gene_ORFName:
CG10895,
CG10895,
Dmel_CG10895,
CG10895,
Dmel_CG10895
EnsemblGenome_TRS:
FBtr0081328,
FBtr0081329,
FBtr0081330,
FBtr0306234,
FBtr0081329,
FBtr0081330
|
| Protein sequencees |
EnsemblGenome_PRO:
FBpp0080861,
FBpp0080860,
FBpp0080862,
FBpp0297344,
FBpp0080862,
FBpp0080861
RefSeq:
NP_477219.1,
NP_724241.1,
NP_001246100.1,
NP_477218.1
|
| Others |
UniRef100:
UniRef100_D3DMK7,
UniRef100_A4V0X0,
UniRef100_O61267
UniRef90:
UniRef90_D3DMK7,
UniRef90_O61267
UniRef50:
UniRef50_D3DMK7,
UniRef50_O61267
UniGene:
Dm.475
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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