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35253 spi

35253

spi

spitz

protein-coding

Drosophila melanogaster

基因描述

Type Description
Definition spitz

研究结论

Date Results Publications
2014-01-18 11:10:00 We provide evidence that miR-8-positive glia express Spitz, a transforming growth factor alpha-like ligand that triggers epidermal growth factor receptor activation to promote neuroepithelial proliferation and neuroblast formation. 24139822
2010-09-20 11:27:00 Study describes crystal structures of s-dEGFR bound to its growth factor ligand Spitz, showing how occupying one binding site in a receptor dimer impairs ligand binding to the second site in an asymmetric complex. 20723758
2010-01-21 00:00:00 Germ cells signal somatic support cells via the Egf class ligand Spitz. 17629483
2010-01-21 00:00:00 Argos inhibits EGFR (DER) signalling without interacting directly with the receptor, but instead by sequestering the DER-activating ligand Spitz 15329724
2010-01-21 00:00:00 Sl PLC gamma is required for endoplasmic reticulum retention of cleaved spi during eye development. 15469842

名称对应

Type IDs
Synonymous CG10334, CT29014, Dmel\CG10334, EP(2)2378, Spi, Spitz, anon-WO0118547.158, l(2)01068, l(2)37Fa, l(2)s3547, s-spi, sSpi
Gene
UniProtKB-ID: SPITZ_DROME, A4V0W1_DROME
UniprotKB: Q01083, A4V0W1
UniParc: UPI000034DF72
EMBL: AY089693, AE014134, M95199, BT044503
EnsemblGenome: FBgn0005672
KO: dme:Dmel_CG10334
Nucleutide sequences
EMBL-CDS: AAF53831.2, AAA28894.1, AAL90431.1, AAN11053.2, AAN11052.2, AAZ66477.1, AAG22442.2, ACH95277.1
Gene_ORFName: CG10334, Dmel_CG10334, CG10334
EnsemblGenome_TRS: FBtr0081267, FBtr0100597, FBtr0081270, FBtr0081269, FBtr0081268, FBtr0081267, FBtr0100597, FBtr0081269, FBtr0081270, FBtr0081268
Protein sequencees
EnsemblGenome_PRO: FBpp0080810, FBpp0080809, FBpp0080808, FBpp0100054, FBpp0080811, FBpp0100054, FBpp0080811, FBpp0080808, FBpp0080810, FBpp0080809
RefSeq: NP_599118.2, NP_599119.2, NP_476909.2, NP_599120.2, NP_001027281.1
Others
UniRef100: UniRef100_Q01083
UniRef90: UniRef90_Q01083
UniRef50: UniRef50_Q01083
UniGene: Dm.4573

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