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35225 Top2

35225

Top2

Topoisomerase 2

protein-coding

Drosophila melanogaster

基因描述

Type Description
Definition Topoisomerase 2

研究结论

Date Results Publications
2016-11-19 11:14:00 The Top2-Mus101 interaction is important for maintaining the fidelity of chromosome segregation during mitosis. 27129233
2015-07-04 15:24:00 These data suggest both that Topoisomerase II is involved in the resolution of heterochromatic DNA entanglements during meiosis I and that these entanglements must be resolved in order to complete meiosis. 25340780
2015-07-04 15:24:00 our results suggest that the previously observed discrepancies in the chromosomal phenotypes elicited by Topo II downregulation in vertebrates might depend on slight differences in Topo II concentration and/or activity 25340516
2011-08-06 10:37:00 Topo II is required to prevent Mod(mdg4)2.2 degradation and, consequently, to stabilize Su(Hw) insulator-mediated chromatin organization 21304601
2010-01-21 00:00:00 Topo II does have some role in mitotic chromatin condensation 14600258

名称对应

Type IDs
Synonymous CG10223, CHRAC, Dmel\CG10223, TOP2, TOPO II, TOPOII, TopII, Topo II, TopoII, dCHRAC, dTopoII, suo, top2, topo II, topoII
Gene
UniProtKB-ID: TOP2_DROME
UniprotKB: P15348
UniParc: UPI00000074DB
EMBL: BT010240, BT150455, AE014134, X61209
EnsemblGenome: FBgn0284220
KO: dme:Dmel_CG10223
Nucleutide sequences
EMBL-CDS: AGB93115.1, AAQ23558.1, CAA43523.1, AAF53802.2, AJP62077.1
Gene_ORFName: CG10223
EnsemblGenome_TRS: FBtr0332320, FBtr0081287
Protein sequencees
EnsemblGenome_PRO: FBpp0304598, FBpp0080825
RefSeq: NP_001260580.1, NP_476760.1
Others
UniRef100: UniRef100_P15348
UniRef90: UniRef90_P15348
UniRef50: UniRef50_P15348
UniGene: Dm.22886

全选

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研究热度

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