| Type | Description |
|---|---|
| Definition | brain tumor |
| Date | Results | Publications |
|---|---|---|
| 2020-05-23 10:46:00 | This study determined the crystal structure of Brat-CC domain (aa 376-511) at 2.5 A, showing that Brat-CC forms an elongated antiparallel dimer through an unconventional CC structure. | 30958583 |
| 2019-01-05 10:46:00 | The tumor suppressor Brat controls neuronal stem cell lineages by inhibiting Deadpan and Zelda. | 29191977 |
| 2018-07-21 11:15:00 | Combinatorial control of messenger RNAs by Pumilio, Nanos and Brain Tumor proteins has been described. | 28318367 |
| 2018-06-30 10:56:00 | Data suggest that brain tumor protein (Brat) promotes midline crossing through directing the localization or stability of Adenomatous polyposis coli-2 (Apc2) at the plus ends of microtubules in navigating commissural axons. | 29617376 |
| 2017-03-04 11:08:00 | results support a novel role for Brat/TRIM3 in maintaining stem cell equilibrium and suppressing tumor growth by regulating NICD nuclear transport | 26893479 |
| Type | IDs |
|---|---|
| Synonymous | BRAT, Brat, CG10719, Cf, Dmel\CG10719, E60, anon-37CDa, fs(2)ltoPM43, l(2)37Cf, l(2)E60, l(2)brat, lincRNA.S1565 |
| Gene |
UniProtKB-ID:
BRAT_DROME,
E8NHB3_DROME,
M9MSJ1_DROME
UniprotKB:
Q8MQJ9,
E8NHB3,
M9MSJ1
UniParc:
UPI0002ADBC60,
UPI0000080298
EMBL:
BT125989,
AY129441,
AB022432,
AF195872,
AE014134,
DQ138866,
AF195873,
AY122207,
AF195870,
AF119332,
AF195871
EnsemblGenome:
FBgn0010300
KO:
dme:Dmel_CG10719
|
| Nucleutide sequences |
EMBL-CDS:
AAF13929.1,
AAM52719.1,
AAS64719.1,
AAM76183.1,
AAF13927.1,
AAN11027.1,
AAF13926.1,
ABA86472.1,
AAF13928.1,
BAA82071.1,
AAF03086.1,
ADX35968.1,
AHN54597.1,
ADV37091.2
Gene_ORFName:
CG10719,
Dmel_CG10719,
CG10719,
CG10719,
Dmel_CG10719
EnsemblGenome_TRS:
FBtr0344846,
FBtr0081160,
FBtr0081158,
FBtr0081159,
FBtr0081160,
FBtr0344846,
FBtr0081159,
FBtr0081158,
FBtr0336627
|
| Protein sequencees |
EnsemblGenome_PRO:
FBpp0080703,
FBpp0311161,
FBpp0089239,
FBpp0080702,
FBpp0311161,
FBpp0080703,
FBpp0089239,
FBpp0080702,
FBpp0307610
RefSeq:
NP_476945.1,
NP_995726.1,
NP_001286083.1,
NP_001188842.2,
NP_599129.1
|
| Others |
UniRef100:
UniRef100_Q8MQJ9,
UniRef100_M9MSJ1
UniRef90:
UniRef90_Q8MQJ9
UniRef50:
UniRef50_Q8MQJ9
UniGene:
Dm.6426
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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