| Type | Description |
|---|---|
| Definition | Bicaudal D |
| Date | Results | Publications |
|---|---|---|
| 2021-04-13 10:11:00 | Coiled-coil registry shifts in the F684I mutant of Bicaudal D result in cargo-independent activation of dynein motility. | 32378283 |
| 2019-03-30 10:07:00 | the RNA is required for robust activation of dynein motility. We show that a cis-acting RNA localisation signal promotes the interaction of Egl with BicD, which licenses the latter protein to recruit dynein and dynactin. Our data support a model for BicD activation based on RNA-induced occupancy of two Egl-binding sites on the BicD dimer. | 29944118 |
| 2019-03-30 10:07:00 | artificially dimerized Egl activates dynein-dynactin-BicD in the absence of mRNA. The ability of mRNA cargo to orchestrate the activation of the mRNP (messenger ribonucleotide protein) complex is an elegant way to ensure that only cargo-bound motors are motile. | 29944116 |
| 2019-02-16 12:00:00 | To study the pathological consequences of BICD2 mutations in vivo, and to address the controversial debate whether two of these mutations are neuron or muscle specific, we generated the first Drosophila model of spinal muscular atrophy-2. | 29528393 |
| 2014-06-14 10:58:00 | Bic-D is also required to transport Chc mRNA into the oocyte and for transport and proper localization of Chc protein to the oocyte cortex. | 24718986 |
| Type | IDs |
|---|---|
| Synonymous | BIC-D, BICD, Bic-D, Bic[D], CG6605, Dmel\CG6605, almond, anon-EST:fe2A11 |
| Gene |
UniProtKB-ID:
BICD_DROME,
M9PDL9_DROME,
M9NDR2_DROME,
M9PDB8_DROME
UniprotKB:
P16568,
M9PDL9,
M9NDR2,
M9PDB8
UniParc:
UPI0002941F49,
UPI0000000F8A,
UPI000237F452
EMBL:
AY069452,
M31684,
X51652,
AE014134
EnsemblGenome:
FBgn0000183
KO:
dme:Dmel_CG6605
|
| Nucleutide sequences |
EMBL-CDS:
AAA28393.1,
CAA35964.1,
AAF53616.1,
AAL39597.1,
AGB93065.1,
AFH03731.1,
AGB93066.1
Gene_ORFName:
CG6605,
CG6605,
Dmel_CG6605,
CG6605,
Dmel_CG6605,
CG6605,
Dmel_CG6605
EnsemblGenome_TRS:
FBtr0330225,
FBtr0081002,
FBtr0081002,
FBtr0330225,
FBtr0305688,
FBtr0330226
|
| Protein sequencees |
EnsemblGenome_PRO:
FBpp0080555,
FBpp0303258,
FBpp0080555,
FBpp0303258,
FBpp0296968,
FBpp0303259
RefSeq:
NP_724056.1,
NP_001260530.1,
NP_001246057.1,
NP_001260531.1
|
| Others |
UniRef100:
UniRef100_M9NDR2,
UniRef100_P16568
UniRef90:
UniRef90_P16568
UniRef50:
UniRef50_P16568
UniGene:
Dm.3232
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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