GPR142 - G protein-coupled receptor 142-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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350383 GPR142

基因描述

Type	Description
Definition	G protein-coupled receptor 142

研究结论

Date	Results	Publications
2017-06-10 10:19:00	e developed GPR142 agonists as insulin secretagogues. In this report, we show the discovery of a selective, potent small-molecule GPR142 antagonist, CLP-3094, and its pharmacological characteristics. These data support targeting this receptor for the treatment of chronic inflammatory diseases.	27807998

名称对应

Type	IDs
Synonymous	GPRg1b, PGR2
Gene	UniProtKB-ID: GP142_HUMAN UniprotKB: Q7Z601 UniParc: UPI00001AA7F1 EMBL: AB196530, AY255622, AY288421 Ensembl: ENSG00000257008 KO: hsa:350383
Nucleutide sequences	EMBL-CDS: BAD97441.1, AAO85134.1, AAP72130.1 Ensembl_TRS: ENST00000335666
Protein sequencees	Ensembl_PRO: ENSP00000335158 RefSeq: NP_001318006.1, NP_861455.1, NP_001318005.1
Others	UniRef100: UniRef100_Q7Z601 UniRef90: UniRef90_Q7Z601 UniRef50: UniRef50_Q7Z601 UniGene: Hs.574368 CCDS: CCDS11698.1

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mRNA

Protein

UniprotKB

Description

Refseq

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Pubmed编号	文献信息	发表日期	相关基因
31010829	Systematic proteomics of endogenous human cohesin reveals an interaction with diverse splicing factors and RNA-binding proteins required for mitotic progression. J Biol Chem Jung-Sik Kim , Xiaoyuan He , Jie Liu , Zhijun Duan , Taeyeon Kim , Julia Gerard , Brian Kim , Manoj M Pillai , William S Lane , William S Noble , Bogdan Budnik , Todd Waldman	2019-05-31	-
27807998	Discovery and pharmacological effects of a novel GPR142 antagonist. J. Recept. Signal Transduct. Res. Michiko Murakoshi , Harumi Kuwabara , Miyuki Nagasaki , Yu Mei Xiong , Jeff D Reagan , Hiroaki Maeda , Futoshi Nara	2017-06-01	-
22889411	Proteomics strategy to identify substrates of LNX, a PDZ domain-containing E3 ubiquitin ligase. J. Proteome Res. Zhengguang Guo , Eli Song , Sucan Ma , Xiaorong Wang , Shijuan Gao , Chen Shao , Siqi Hu , Lulu Jia , Rui Tian , Tao Xu , Youhe Gao	2012-10-05	PQBP1, PKDREJ, LRRC3B, ADRA1D, EXOC8, CTNND2, CTSO, CXADR, ABCA1, GJD4, SDK1, LNX2, PDZRN3, DOCK9, CDC42EP4, GAS2L2, CLDN17, MDGA1, GIPR, ARHGEF16, GRIN1, ABR, PDZRN4, HUNK, HTR2B, GPR142, ILF3, KCNA4, INSC, SHISA2, ARHGAP6, ARVCF, CITED1, NRCAM, BPIFA1, ABCB1, SLC6A15, PBK, PTGIR, CGN, LGR6, BCR, SSTR3, STRN, TSC2, TYRO3, UBE2D2, VRK2, WNT8A, NUP37, LNX1, PKP4, CBX4, TNFRSF18, KALRN, CLDN2, CLDN1, SLC6A5, ORMDL3, JOSD1
18029348	Toward a confocal subcellular atlas of the human proteome. Mol Cell Proteomics Laurent Barbe , Emma Lundberg , Per Oksvold , Anna Stenius , Erland Lewin , Erik BjÃ¶rling , Anna Asplund , Fredrik PontÃ©n , Hjalmar Brismar , Mathias UhlÃ©n , Helene Andersson-Svahn	2008-03-01	-
15845401	Molecular cloning and characterization of a novel Gq-coupled orphan receptor GPRg1 exclusively expressed in the central nervous system. Biochem. Biophys. Res. Commun. Ayako Matsuo , Shun-ichiro Matsumoto , Mamoru Nagano , Koh-hei Masumoto , Jun Takasaki , Mitsuyuki Matsumoto , Masato Kobori , Masao Katoh , Yasufumi Shigeyoshi	2005-05-27	Gpr139, Gpr139, GPR139, GPR142
14623098	Seven evolutionarily conserved human rhodopsin G protein-coupled receptors lacking close relatives. FEBS Lett. Robert Fredriksson , PÃ¤r J HÃ¶glund , David E I Gloriam , Malin C LagerstrÃ¶m , Helgi B SchiÃ¶th	2003-11-20	-
12679517	The G protein-coupled receptor repertoires of human and mouse. Proc. Natl. Acad. Sci. U.S.A. Demetrios K Vassilatis , John G Hohmann , Hongkui Zeng , Fusheng Li , Jane E Ranchalis , Marty T Mortrud , Analisa Brown , Stephanie S Rodriguez , John R Weller , Abbie C Wright , John E Bergmann , George A Gaitanaris	2003-04-15	Gpr153, Gpr137, Ffar4, Lgr4, Grm2, Grm5, Grm6, Grm7, Drd1, Drd5, Gpr37l1, Ghsr, Taar2, Taar4, Gpr139, Adgrb3, Gpr142, Gpr149, Adgrb2, Hcrtr1, Gpr26, Adgrg4, Npffr1, Gpr68, Gpr150, Gpr20, Adgrg7, Gpr151, Gpr161, Tpra1, Rxfp4, Gabbr2, Adgrd1, C130060K24Rik, Mtnr1b, Gpr101, Pgr15l, Grm4, Gpr4, Gpr82, Sctr, Npsr1, Adgrl3, Gpr183, Lgr6, Adgrl1, Gpr21, Opn5, Gpr141, Gpr176, Rxfp1, Adgrf3, Lpar5, Gipr, Adgrg5, Adgrf2, Gpr62, Taar9, Adgra1, Gpr17, Gpr155, Gpr137c, Gpr173, Gpr39, Gpr22, Lpar4, Glp2r, GPR146, MRGPRE, GPR139, GPR151, ADGRG4, GPR155, ADGRF3, GPR156, ADGRG5, OPN5, ADGRF4, ADGRF5, ADGRG3, ADGRF2, ADGRF1, ADGRD1, GPR137C, GPR150, ADGRE4P, FFAR4, GPR148, GPR149, ADGRD2, GPR142, GPR141, MRGPRG, NPSR1, GPR153, GPR152, GPR135, ADGRA1
12477932	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc. Natl. Acad. Sci. U.S.A. Robert L Strausberg , Elise A Feingold , Lynette H Grouse , Jeffery G Derge , Richard D Klausner , Francis S Collins , Lukas Wagner , Carolyn M Shenmen , Gregory D Schuler , Stephen F Altschul , Barry Zeeberg , Kenneth H Buetow , Carl F Schaefer , Narayan K Bhat , Ralph F Hopkins , Heather Jordan , Troy Moore , Steve I Max , Jun Wang , Florence Hsieh , Luda Diatchenko , Kate Marusina , Andrew A Farmer , Gerald M Rubin , Ling Hong , Mark Stapleton , M Bento Soares , Maria F Bonaldo , Tom L Casavant , Todd E Scheetz , Michael J Brownstein , Ted B Usdin , Shiraki Toshiyuki , Piero Carninci , Christa Prange , Sam S Raha , Naomi A Loquellano , Garrick J Peters , Rick D Abramson , Sara J Mullahy , Stephanie A Bosak , Paul J McEwan , Kevin J McKernan , Joel A Malek , Preethi H Gunaratne , Stephen Richards , Kim C Worley , Sarah Hale , Angela M Garcia , Laura J Gay , Stephen W Hulyk , Debbie K Villalon , Donna M Muzny , Erica J Sodergren , Xiuhua Lu , Richard A Gibbs , Jessica Fahey , Erin Helton , Mark Ketteman , Anuradha Madan , Stephanie Rodrigues , Amy Sanchez , Michelle Whiting , Anup Madan , Alice C Young , Yuriy Shevchenko , Gerard G Bouffard , Robert W Blakesley , Jeffrey W Touchman , Eric D Green , Mark C Dickson , Alex C Rodriguez , Jane Grimwood , Jeremy Schmutz , Richard M Myers , Yaron S N Butterfield , Martin I Krzywinski , Ursula Skalska , Duane E Smailus , Angelique Schnerch , Jacqueline E Schein , Steven J M Jones , Marco A Marra , Mammalian Gene Collection Program Team	2002-12-24	-

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