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35007 Mhc

35007

Mhc

Myosin heavy chain

protein-coding

Drosophila melanogaster

基因描述

Type Description
Definition Myosin heavy chain

研究结论

Date Results Publications
2021-02-27 13:45:00 Alternative N-terminal regions of Drosophila myosin heavy chain II regulate communication of the purine binding loop with the essential light chain. 32817166
2020-08-29 12:47:00 Atypical Myosin Tunes Dendrite Arbor Subdivision. 32155441
2020-07-18 11:29:00 Hypertrophic cardiomyopathy causative mutation R249Q alters flight muscle contractility and flight performance. 30950055
2020-07-04 10:20:00 Here we report the first x-ray crystal structure of an insect myosin: the D melanogaster skeletal muscle myosin II embryonic isoform (EMB). Using our system for recombinant expression of myosin heavy chain (MHC) proteins in whole transgenic flies, we prepared and crystallized stable proteolytic S1-like fragments containing the entire EMB motor domain bound to an essential light chain 31786266
2020-01-04 10:24:00 Findings indicate that the Freeman Sheldon Syndrome (FSS) contracture syndrome mutations lead to muscle structural defects and functional deficits in Drosophila, possibly mediated by the reduced ATPase activity of the mutant Myosin heavy chain (MHC) proteins. 30826400

名称对应

Type IDs
Synonymous Bsh, CG17927, DROMHC, Dm II, DmMHC, Dmel\CG17927, DroMII, FBgn0002741, Ifm(2)2, Ifm(2)RU1, MHC, MRP, Mhc36B, Mrp, MyHC, Myo, Myo6, Nup, Sht, Stp, chr2L:16765388..16765564, chr2L:16781880..16782040, ifm(2)2, ifm(2)RU1, ifm(2)RU2, l(2)36Ae, l(2)M66, l(2)k10423, mMHC, mhc, sMHC
Gene
UniProtKB-ID: MYSA_DROME, M9NF46_DROME, E1JHJ4_DROME, A0A0S0WIH4_DROME, E1JHJ5_DROME, E1JHJ3_DROME, M9NEP1_DROME, M9ND95_DROME, M9NCU7_DROME
UniprotKB: P05661, M9NF46, E1JHJ4, A0A0S0WIH4, E1JHJ5, E1JHJ3, M9NEP1, M9ND95, M9NCU7
UniParc: UPI0000DAC9A5, UPI0000DAC99B, UPI0000DAC9A4, UPI0000DAC99A, UPI0000DAC9A6, UPI0000084770, UPI000008476E, UPI0004F13E01, UPI000008476D, UPI000237F442, UPI0000DAC99C, UPI0000DAC99F, UPI0001C00029, UPI0001C00028, UPI0000DAC99D, UPI0000DAC9A0, UPI0000084768, UPI000008476C, UPI0000084773, UPI000237F43E, UPI0000084769, UPI000008476B, UPI000060018D, UPI0000084772, UPI0000DAC9A3, UPI000237F43F, UPI0000DAC9A1, UPI000008476F, UPI0000084771, UPI0000DAC99E, UPI000008476A, UPI0000DAC9A2, UPI00002285D6
EMBL: J02788, M13360, X53155, M61229, X60196, AE014134
EnsemblGenome: FBgn0264695
KO: dme:Dmel_CG17927
Nucleutide sequences
EMBL-CDS: CAA42754.1, CAA37311.1, AAA28709.1, AAN10966.1, AAF53566.4, CAA42752.1, AAN10970.1, AAA28706.1, CAA37310.1, AAA28707.1, CAA42753.1, AAN10963.1, AAN10964.1, AAN10962.1, AAN10965.1, AAA28687.1, AAN10959.1, AAA28708.1, AAN10969.1, AAN10967.1, CAA37309.1, AAN10961.1, AAN10960.1, AAN10968.1, AAA28686.1, CAA37308.1, AFH03722.1, ACZ94276.1, ALI30210.1, ACZ94278.1, ACZ94277.1, AFH03724.1, AFH03725.1, AFH03723.1
Gene_ORFName: CG17927, Dmel_CG17927, CG17927, Dmel_CG17927, CG17927, Dmel_CG17927, CG17927, CG17927, Dmel_CG17927, CG17927, Dmel_CG17927, Dmel_CG17927, CG17927, CG17927, Dmel_CG17927, Dmel_CG17927, CG17927
EnsemblGenome_TRS: FBtr0301828, FBtr0080896, FBtr0080897, FBtr0080895, FBtr0080905, FBtr0080902, FBtr0080898, FBtr0080899, FBtr0080900, FBtr0080901, FBtr0080907, FBtr0080906, FBtr0307492, FBtr0080903, FBtr0307493, FBtr0301827, FBtr0346712, FBtr0301829, FBtr0080895, FBtr0301828, FBtr0307495, FBtr0307496, FBtr0307494
Protein sequencees
EnsemblGenome_PRO: FBpp0080462, FBpp0080456, FBpp0298827, FBpp0080452, FBpp0080455, FBpp0080459, FBpp0080460, FBpp0080453, FBpp0291042, FBpp0080458, FBpp0080457, FBpp0080464, FBpp0080463, FBpp0080454, FBpp0298828, FBpp0291041, FBpp0312323, FBpp0291043, FBpp0291042, FBpp0080452, FBpp0298830, FBpp0298831, FBpp0298829
RefSeq: NP_001246049.1, NP_001162990.1, NP_724009.1, NP_723999.1, NP_001246048.1, NP_724007.1, NP_724000.1, NP_001303327.1, NP_724006.1, NP_001246051.1, NP_724001.1, NP_724003.1, NP_724004.1, NP_724005.1, NP_523587.4, NP_724010.1, NP_724008.1, NP_001162991.1, NP_001246050.1, NP_724002.2, NP_001162992.1
Others
UniRef100: UniRef100_P05661, UniRef100_E1JHJ4, UniRef100_E1JHJ5, UniRef100_M9NCU7, UniRef100_E1JHJ3, UniRef100_A0A0S0WIH4, UniRef100_M9NEP1, UniRef100_M9ND95, UniRef100_M9NF46
UniRef90: UniRef90_P05661, UniRef90_P05661-19
UniRef50: UniRef50_P05661, UniRef50_P05661-2
UniGene: Dm.2761

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