| Type | Description |
|---|---|
| Definition | Ku80 |
| Date | Results | Publications |
|---|---|---|
| 2020-03-21 10:39:00 | partial loss of function of Ku80 in these neurons through CRISPR/Cas9-mediated ablation or small RNAs-mediated knockdown suppressed the apoptotic pathway. Thus, partial inhibition of the overactivated Ku80-dependent DNA repair pathway is a promising therapeutic approach in C9ORF72-ALS/FTD. | 31019093 |
| 2015-12-19 10:13:00 | Genome-wide gene-set-based analysis and follow-up studies in Drosophila and humans generated independent evidence for the involvement of XRCC5 (Ku80) in alcohol dependence | 25035082 |
| 2014-09-06 11:37:00 | specific regulation of ku80 expression by UTX | 24265704 |
| 2010-01-21 00:00:00 | Decrease in gene dosage causes a sharp increase in the frequency of HeT-A and TART attachments to a broken chromosome end and in terminal DNA elongation by gene conversion. | 15781709 |
| 2010-01-21 00:00:00 | Role for Ku subunits in the regulation of sperm individualization. | 17418821 |
| Type | IDs |
|---|---|
| Synonymous | BG:DS09217.6, CG18801, DmKu80, Dmel\CG18801, KU80, Ku, ku80 |
| Gene |
UniProtKB-ID:
Q9I7M8_DROME
UniprotKB:
Q9I7M8
UniParc:
UPI0000076330
EMBL:
AE014134
EnsemblGenome:
FBgn0041627
KO:
dme:Dmel_CG18801
|
| Nucleutide sequences |
EMBL-CDS:
AAG22435.1
Gene_ORFName:
CG18801,
Dmel_CG18801
EnsemblGenome_TRS:
FBtr0080763
|
| Protein sequencees |
EnsemblGenome_PRO:
FBpp0080322
RefSeq:
NP_609767.2
|
| Others |
UniRef100:
UniRef100_Q9I7M8
UniRef90:
UniRef90_Q9I7M8
UniRef50:
UniRef50_Q9I7M8
UniGene:
Dm.3289
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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