| Type | Description |
|---|---|
| Definition | immunoglobulin heavy constant alpha 1 |
| Date | Results | Publications |
|---|---|---|
| 2019-08-10 10:18:00 | is s immune component extensively expressed in mucosa and epidermis, which are responsible for the first line of host defense. | 30529003 |
| 2019-04-13 10:44:00 | Although IgAN and HSPN remain difficult to differentiate, s-Gd-IgA1 elevation and m-Gd-IgA1 deposition are reliable diagnostic factors that reflect IgAN severity. Serum-Gd-IgA1 could serve as a predictor of renal outcomes in IgAN. Thus, Gd-IgA1 could be significant biomarker for patients with IgAN | 30388165 |
| 2018-08-11 10:40:00 | IL-17 might participate in IgA nephropathy pathogenesis by influencing the production and glycosylation of IgA1 in B-cells. | 29299950 |
| 2017-05-20 13:28:00 | The terminal glycosylation of secreted IgA1 was altered in response to TGFbeta1. TGFbeta1 stimulation significantly decreased the mRNA levels of C1GalT1 and Cosmc. TGFbeta1 may be key in controlling the glycosylation of IgA1, in part via the downregulation of C1GalT1 and Cosmc. | 28035353 |
| 2016-08-06 11:48:00 | In IgA nephropathy, increased APRIL is accompanied by elevated expression of its receptors in B-lymphocytes, which induces overproduction of galactose-deficient-IgA1. | 26986150 |
| Type | IDs |
|---|---|
| Synonymous | IgA1 |
| Gene | |
| Nucleutide sequences | |
| Protein sequencees | |
| Others |
UniGene:
Hs.699841
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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