| Type | Description |
|---|---|
| Definition | Cullin 3 |
| Date | Results | Publications |
|---|---|---|
| 2019-10-26 12:39:00 | Study identified insomniac (inc), a putative adaptor for the Cullin-3 (Cul3) ubiquitin ligase complex, which together with Cul3 is essential for normal sleep regulation. Interestingly, Inc and Cul3 rapidly accumulate at postsynaptic compartments following acute receptor inhibition and are required for a local increase in mono-ubiquitination. | 31278365 |
| 2017-09-30 12:10:00 | CRL3(GCL) promotes primordial germ cell fate by mediating degradation of Torso, a receptor tyrosine kinase (RTK) and major determinant of somatic cell fate. | 28743001 |
| 2017-02-04 10:47:00 | Data show that insomniac protein (INC) recognize its potential partners Cul3 and dGRASP. | 27678190 |
| 2013-06-08 12:56:00 | A Cul-3-BTB ubiquitylation pathway regulates junctional levels and asymmetry of core planar polarity proteins. | 23487316 |
| 2013-03-23 10:31:00 | these results establish inc and Cul3 as important new players in setting the sleep homeostat and a dopaminergic arousal pathway in Drosophila. | 23055946 |
| Type | IDs |
|---|---|
| Synonymous | BG:DS07851.2, CG11861, CG31829, CG42616, CUL-3, CUL3, Cul-3, Cullin3, DMcul-3, Dmel\CG42616, Dmel_CG11861, Dmel_CG31829, br34, cul-3, cul3, dCul-3, dCul3, gft, gft/dCul-3, guftagu, l(2)06430, l(2)35Cd, l(2)br34, l35Cd, mds |
| Gene |
UniProtKB-ID:
Q9V475_DROME,
Q8IP45_DROME
UniprotKB:
Q9V475,
Q8IP45
UniParc:
UPI0000079E1F,
UPI0001BFFF8D
EMBL:
AE014134,
BT021406,
BT133182
EnsemblGenome:
FBgn0261268
KO:
dme:Dmel_CG42616
|
| Nucleutide sequences |
EMBL-CDS:
AAX33554.1,
AAN10895.2,
AAF53450.1,
AAF53451.1,
AFA28423.1,
AAN10896.2
Gene_ORFName:
Dmel_CG42616,
CG42616,
Dmel_CG42616,
CG42616
EnsemblGenome_TRS:
FBtr0302156,
FBtr0302157,
FBtr0302158,
FBtr0302159
|
| Protein sequencees |
EnsemblGenome_PRO:
FBpp0291367,
FBpp0291366,
FBpp0291368,
FBpp0291369
RefSeq:
NP_723909.2,
NP_723908.2,
NP_523573.1,
NP_723907.1
|
| Others |
UniRef100:
UniRef100_Q8IP45,
UniRef100_Q9V475
UniRef90:
UniRef90_Q8IP45,
UniRef90_Q9V475
UniRef50:
UniRef50_Q8IP45,
UniRef50_Q9V475
UniGene:
Dm.18043
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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