| Type | Description |
|---|---|
| Definition | insulin like growth factor binding protein 4 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-27 14:40:00 | Increase of circulating IGFBP-4 following genotoxic stress and its implication for senescence. | 32223893 |
| 2020-03-14 11:53:00 | IGFBP-4 released from glia-like human mesenchymal stem cells (ghMSCs) may serve as one of the key neuronal survival factors secreted from ghMSCs. | 31081524 |
| 2020-02-29 11:04:00 | Birth weight and length Z-scores were negatively associated with Z-scores of intact IGFBP-4, PAPP-A, and PAPP-A2 levels | 31401027 |
| 2020-02-29 10:47:00 | Results revealed that the differentially expressed IGFBP4 between aged and young samples is related to the process of aging. | 31601169 |
| 2019-07-13 11:34:00 | Igfbp4 down-regulation significantly correlated with EZH2 overexpression and poor survivals of HCC patients. IGFBP4 stimulated AKT/EZH2 phosphorylation to abrogate H3K27me3-mediated silencing, forming a reciprocal feedback loop that suppressed core transcription factor networks (FOXA1/HNF1A/HNF4A/KLF9/NR1H4) for normal liver homeostasis. | 29992318 |
| Type | IDs |
|---|---|
| Synonymous | BP-4, HT29-IGFBP, IBP4, IGFBP-4 |
| Gene |
UniProtKB-ID:
IBP4_HUMAN,
A0A024R1U8_HUMAN
UniprotKB:
P22692,
A0A024R1U8
UniParc:
UPI0000035977,
UPI00017A884F
EMBL:
AY442346,
CH471152,
BT019891,
M38177,
M62403,
BT019892,
BC016041,
Y12508,
U20982,
AK304572,
AC018629
Ensembl:
ENSG00000141753
KO:
hsa:3487
|
| Nucleutide sequences |
EMBL-CDS:
CAA73110.1,
AAV38694.1,
AAV38695.1,
AAR05443.1,
EAW60664.1,
AAB06189.1,
AAH16041.1,
BAG65363.1,
AAA62670.1,
EAW60665.1
Gene_ORFName:
hCG_1643839
Ensembl_TRS:
ENST00000269593
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000269593
RefSeq:
NP_001543.2
|
| Others |
UniRef100:
UniRef100_P22692
UniRef90:
UniRef90_P22692
UniRef50:
UniRef50_P22692
UniGene:
Hs.462998
CCDS:
CCDS11367.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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