| Type | Description |
|---|---|
| Definition | rickets |
| Date | Results | Publications |
|---|---|---|
| 2017-09-09 12:26:00 | In Drosophila, rk function is required for the normal maturation of the fly's cuticular hydrocarbon (CH) profile, with flies mutant for rk function showing dramatically elevated levels of CHs. This effect is mostly abrogated by mutations in the Delta9 desaturase encoded by the desaturase1 gene, suggesting that desaturase1 acts downstream of rk. | 27794461 |
| 2017-08-12 11:36:00 | 2 alleles of the gene rickets (rk) encoding a G-protein-coupled receptor were isolated. The rk alleles result in border cell migration defects in a significant fraction of egg chambers. The rk receptor appears to regulate detachment and polarity of the border cell cluster coordinating processes within the cells of the cluster themselves. | 27130192 |
| 2013-05-18 10:30:00 | Membrane-anchored bursicon constructs were generated that can activate or inhibit membrane rk signaling. | 23340494 |
| 2010-01-21 00:00:00 | Bursicon is a heterodimeric cystine knot protein that activates G protein-coupled receptor LGR2. | 15703293 |
| 2010-01-21 00:00:00 | rickets appears to encode a component of the bursicon response pathway | 12151362 |
| Type | IDs |
|---|---|
| Synonymous | BG:DS00180.13, CG8930, CT25644, DLGR-2, DLGR2, Dmel\CG8930, LGR2, Lgr2, lgr2, rk/CG8930 |
| Gene |
UniProtKB-ID:
Q7KTA0_DROME
UniprotKB:
Q7KTA0
UniParc:
UPI00000074AC
EMBL:
AE014134
EnsemblGenome:
FBgn0003255
KO:
dme:Dmel_CG8930
|
| Nucleutide sequences |
EMBL-CDS:
AAF53367.3
Gene_ORFName:
CG8930,
Dmel_CG8930
EnsemblGenome_TRS:
FBtr0080610
|
| Protein sequencees |
EnsemblGenome_PRO:
FBpp0080183
RefSeq:
NP_476702.1
|
| Others |
UniRef100:
UniRef100_Q7KTA0
UniRef90:
UniRef90_Q7KTA0
UniRef50:
UniRef50_Q7KTA0
UniGene:
Dm.6481
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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