| Type | Description |
|---|---|
| Definition | actin related protein 2/3 complex inhibitor |
| Date | Results | Publications |
|---|---|---|
| 2018-02-10 10:37:00 | is down-regulated in breast cancer cells and predicts poor prognosis in breast cancer patients. Data suggest that restoration of duanyu37IN in breast cancer cells suppresses cell proliferation, colony formation, cell cycle distribution, invasion in vitro, and tumorigenesis in vivo (xenograft experiments in nude mice); Arpin acts as tumor suppressor in breast cancer and is associated with inhibition of Akt signaling. | 28531800 |
| 2017-10-28 13:06:00 | Low Arpin levels are associated with clinicopathological variables and a poor prognosis in gastric cancer patients | 28293092 |
| 2017-01-14 11:12:00 | Data reveal that Arpin is comprised of an elongated globular core from which the C-terminal tail extends as a linear peptide, thus forming a primary epitope that is readily available to tether Arpin to interacting proteins. | 26774128 |
| 2017-01-14 10:05:00 | Arpin downregulation may contribute to the initiation and development of breast cancer metastasis. | 26648569 |
| 2016-01-30 11:11:00 | Arpin protein affects the expression of tight junction proteins and may have an impact on bacterial translocation in severe acute pancreatitis. | 25892881 |
| Type | IDs |
|---|---|
| Synonymous | C15orf38 |
| Gene |
UniProtKB-ID:
ARPIN_HUMAN,
H0YMP5_HUMAN
UniprotKB:
Q7Z6K5,
H0YMP5
UniParc:
UPI0001EE4156,
UPI0000161A90,
UPI00005A6223
EMBL:
AK000495,
AC027176,
BC053602,
AC018988
Ensembl:
ENSG00000242498
KO:
hsa:348110
|
| Nucleutide sequences |
EMBL-CDS:
AAH53602.1
Ensembl_TRS:
ENST00000357484,
ENST00000460685
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000350075,
ENSP00000453687
RefSeq:
NP_001269309.1,
NP_872422.1
|
| Others |
UniRef100:
UniRef100_Q7Z6K5
UniRef90:
UniRef90_Q7Z6K5
UniRef50:
UniRef50_Q7Z6K5
UniGene:
Hs.744890
CCDS:
CCDS42080.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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