| Type | Description |
|---|---|
| Definition | ankyrin repeat and death domain containing 1A |
| Date | Results | Publications |
|---|---|---|
| 2020-05-02 12:38:00 | Results provide evidence that rs34988193 is a deleterious germline variant present in ANKDD1a associated with poor outcomes of patients with low grade glioma. | 30651372 |
| 2019-03-16 12:26:00 | ANKDD1A is a functional tumor suppressor gene, especially in the hypoxia microenvironment. ANKDD1A directly interacts with FIH1 and inhibits the transcriptional activity of HIF1alpha by upregulating FIH1. ANKDD1A decreases the half-life of HIF1alpha by upregulating FIH1, decreases glucose uptake and lactate production, inhibits glioblastoma multiforme (GBM) autophagy, and induces apoptosis in GBM cells under hypoxia | 30082910 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
AKD1A_HUMAN
UniprotKB:
Q495B1
UniParc:
UPI0001C2FAC9,
UPI0001C2FAC8,
UPI0001C2FACA,
UPI0000D79C72
EMBL:
BC101275,
AC069368,
AK075298,
AK098736,
BC101273,
BC101274
Ensembl:
ENSG00000166839
KO:
hsa:348094
|
| Nucleutide sequences |
EMBL-CDS:
AAI01275.1,
BAC05399.1,
AAI01274.1,
AAI01276.1,
BAC11532.1
Ensembl_TRS:
ENST00000319580
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000325895
RefSeq:
NP_874362.3
|
| Others |
UniRef100:
UniRef100_Q495B1
UniRef90:
UniRef90_Q495B1
UniRef50:
UniRef50_Q495B1
UniGene:
Hs.207157
CCDS:
CCDS10197.2
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 30651372 |
Mol Cancer Res Ajay Chatrath , Manjari Kiran , Pankaj Kumar , Aakrosh Ratan , Anindya Dutta |
2019-05-01 | - |
| 30082910 |
Oncogene Jianbo Feng , Yan Zhang , Xiaoling She , Yingnan Sun , Li Fan , Xing Ren , Haijuan Fu , Changhong Liu , Peiyao Li , Chunhua Zhao , Qiang Liu , Qing Liu , Guiyuan Li , Minghua Wu |
2019-01-01 | - |
| 28514442 |
Architecture of the human interactome defines protein communities and disease networks. Nature Edward L Huttlin , Raphael J Bruckner , Joao A Paulo , Joe R Cannon , Lily Ting , Kurt Baltier , Greg Colby , Fana Gebreab , Melanie P Gygi , Hannah Parzen , John Szpyt , Stanley Tam , Gabriela Zarraga , Laura Pontano-Vaites , Sharan Swarup , Anne E White , Devin K Schweppe , Ramin Rad , Brian K Erickson , Robert A Obar , K G Guruharsha , Kejie Li , Spyros Artavanis-Tsakonas , Steven P Gygi , J Wade Harper |
2017-05-25 | - |
| 26638075 |
A Dynamic Protein Interaction Landscape of the Human Centrosome-Cilium Interface. Cell Gagan D Gupta , Ãtienne Coyaud , João Gonçalves , Bahareh A Mojarad , Yi Liu , Qianzhu Wu , Ladan Gheiratmand , David Comartin , Johnny M Tkach , Sally W T Cheung , Mikhail Bashkurov , Monica Hasegan , James D Knight , Zhen-Yuan Lin , Markus Schueler , Friedhelm Hildebrandt , Jason Moffat , Anne-Claude Gingras , Brian Raught , Laurence Pelletier |
2015-12-03 |
TANK,
SRA1,
LOC100129118,
TROAP,
PIGK,
WASH1,
DNAJB6,
LOC100506055,
TMEM35B,
OCLN,
LOC100507703,
ERVK3-1,
RBM14-RBM4,
COMMD3-BMI1,
UBA2,
SAE1,
ABCC5,
TIMM23B,
SCAMP2,
SCAMP3,
ARPC3,
ACTR3,
ACTR2,
NUBP2,
TSFM,
RAD50,
KIF20A,
PREB,
ACTR1B,
ACTR1A,
PDIA6,
BCAP31,
SUGP2,
CEBPZ,
ATP6AP2,
LPCAT3,
WASF2,
CDK2,
TENM1,
TXNDC9,
CDK4,
ALG3,
PRMT3,
PSME3,
MPHOSPH9,
CDK5,
TRIM13,
FLOT1,
PSMD14,
MFSD10,
STX6,
DCAF7,
STAM2,
ZMPSTE24,
STUB1,
SIGMAR1,
BET1,
DNAJA2,
PAK4,
KATNB1,
RTN3,
TNIP1,
EMC8,
CNPY2,
TFG,
TUBA1B,
TUBB4A,
TUBB4B,
NDRG1,
NDC80,
NSA2,
PGRMC2,
TUBGCP3,
SEC24B,
EMG1,
MCRS1,
TAB1,
BAIAP2,
PIBF1,
PPIH,
ZNHIT1,
PFDN6,
CLGN,
SLC25A17,
NXF1,
SEC23B,
SEC23A,
VAT1,
NCOA2,
HYOU1,
IPO8,
IPO7,
NEBL,
DCTN2,
PRDX4,
ARL6IP5,
AGPAT1,
RPP38,
CCT7
|
| 26186194 |
The BioPlex Network: A Systematic Exploration of the Human Interactome. Cell Edward L Huttlin , Lily Ting , Raphael J Bruckner , Fana Gebreab , Melanie P Gygi , John Szpyt , Stanley Tam , Gabriela Zarraga , Greg Colby , Kurt Baltier , Rui Dong , Virginia Guarani , Laura Pontano Vaites , Alban Ordureau , Ramin Rad , Brian K Erickson , Martin Wühr , Joel Chick , Bo Zhai , Deepak Kolippakkam , Julian Mintseris , Robert A Obar , Tim Harris , Spyros Artavanis-Tsakonas , Mathew E Sowa , Pietro De Camilli , Joao A Paulo , J Wade Harper , Steven P Gygi |
2015-07-16 | - |
| 22139419 |
New gene functions in megakaryopoiesis and platelet formation. Nature Christian Gieger , Aparna Radhakrishnan , Ana Cvejic , Weihong Tang , Eleonora Porcu , Giorgio Pistis , Jovana Serbanovic-Canic , Ulrich Elling , Alison H Goodall , Yann Labrune , Lorna M Lopez , Reedik Mägi , Stuart Meacham , Yukinori Okada , Nicola Pirastu , Rossella Sorice , Alexander Teumer , Katrin Voss , Weihua Zhang , Ramiro Ramirez-Solis , Joshua C Bis , David Ellinghaus , Martin Gögele , Jouke-Jan Hottenga , Claudia Langenberg , Peter Kovacs , Paul F O'Reilly , So-Youn Shin , Tõnu Esko , Jaana Hartiala , Stavroula Kanoni , Federico Murgia , Afshin Parsa , Jonathan Stephens , Pim van der Harst , C Ellen van der Schoot , Hooman Allayee , Antony Attwood , Beverley Balkau , François Bastardot , Saonli Basu , Sebastian E Baumeister , Ginevra Biino , Lorenzo Bomba , Amélie Bonnefond , François Cambien , John C Chambers , Francesco Cucca , Pio D'Adamo , Gail Davies , Rudolf A de Boer , Eco J C de Geus , Angela Döring , Paul Elliott , Jeanette Erdmann , David M Evans , Mario Falchi , Wei Feng , Aaron R Folsom , Ian H Frazer , Quince D Gibson , Nicole L Glazer , Chris Hammond , Anna-Liisa Hartikainen , Susan R Heckbert , Christian Hengstenberg , Micha Hersch , Thomas Illig , Ruth J F Loos , Jennifer Jolley , Kay Tee Khaw , Brigitte Kühnel , Marie-Christine Kyrtsonis , Vasiliki Lagou , Heather Lloyd-Jones , Thomas Lumley , Massimo Mangino , Andrea Maschio , Irene Mateo Leach , Barbara McKnight , Yasin Memari , Braxton D Mitchell , Grant W Montgomery , Yusuke Nakamura , Matthias Nauck , Gerjan Navis , Ute Nöthlings , Ilja M Nolte , David J Porteous , Anneli Pouta , Peter P Pramstaller , Janne Pullat , Susan M Ring , Jerome I Rotter , Daniela Ruggiero , Aimo Ruokonen , Cinzia Sala , Nilesh J Samani , Jennifer Sambrook , David Schlessinger , Stefan Schreiber , Heribert Schunkert , James Scott , Nicholas L Smith , Harold Snieder , John M Starr , Michael Stumvoll , Atsushi Takahashi , W H Wilson Tang , Kent Taylor , Albert Tenesa , Swee Lay Thein , Anke Tönjes , Manuela Uda , Sheila Ulivi , Dirk J van Veldhuisen , Peter M Visscher , Uwe Völker , H-Erich Wichmann , Kerri L Wiggins , Gonneke Willemsen , Tsun-Po Yang , Jing Hua Zhao , Paavo Zitting , John R Bradley , George V Dedoussis , Paolo Gasparini , Stanley L Hazen , Andres Metspalu , Mario Pirastu , Alan R Shuldiner , L Joost van Pelt , Jaap-Jan Zwaginga , Dorret I Boomsma , Ian J Deary , Andre Franke , Philippe Froguel , Santhi K Ganesh , Marjo-Riitta Jarvelin , Nicholas G Martin , Christa Meisinger , Bruce M Psaty , Timothy D Spector , Nicholas J Wareham , Jan-Willem N Akkerman , Marina Ciullo , Panos Deloukas , Andreas Greinacher , Steve Jupe , Naoyuki Kamatani , Jyoti Khadake , Jaspal S Kooner , Josef Penninger , Inga Prokopenko , Derek Stemple , Daniela Toniolo , Lorenz Wernisch , Serena Sanna , Andrew A Hicks , Augusto Rendon , Manuel A Ferreira , Willem H Ouwehand , Nicole Soranzo |
2011-11-30 | - |
| 12477932 |
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc. Natl. Acad. Sci. U.S.A. Robert L Strausberg , Elise A Feingold , Lynette H Grouse , Jeffery G Derge , Richard D Klausner , Francis S Collins , Lukas Wagner , Carolyn M Shenmen , Gregory D Schuler , Stephen F Altschul , Barry Zeeberg , Kenneth H Buetow , Carl F Schaefer , Narayan K Bhat , Ralph F Hopkins , Heather Jordan , Troy Moore , Steve I Max , Jun Wang , Florence Hsieh , Luda Diatchenko , Kate Marusina , Andrew A Farmer , Gerald M Rubin , Ling Hong , Mark Stapleton , M Bento Soares , Maria F Bonaldo , Tom L Casavant , Todd E Scheetz , Michael J Brownstein , Ted B Usdin , Shiraki Toshiyuki , Piero Carninci , Christa Prange , Sam S Raha , Naomi A Loquellano , Garrick J Peters , Rick D Abramson , Sara J Mullahy , Stephanie A Bosak , Paul J McEwan , Kevin J McKernan , Joel A Malek , Preethi H Gunaratne , Stephen Richards , Kim C Worley , Sarah Hale , Angela M Garcia , Laura J Gay , Stephen W Hulyk , Debbie K Villalon , Donna M Muzny , Erica J Sodergren , Xiuhua Lu , Richard A Gibbs , Jessica Fahey , Erin Helton , Mark Ketteman , Anuradha Madan , Stephanie Rodrigues , Amy Sanchez , Michelle Whiting , Anup Madan , Alice C Young , Yuriy Shevchenko , Gerard G Bouffard , Robert W Blakesley , Jeffrey W Touchman , Eric D Green , Mark C Dickson , Alex C Rodriguez , Jane Grimwood , Jeremy Schmutz , Richard M Myers , Yaron S N Butterfield , Martin I Krzywinski , Ursula Skalska , Duane E Smailus , Angelique Schnerch , Jacqueline E Schein , Steven J M Jones , Marco A Marra , Mammalian Gene Collection Program Team |
2002-12-24 | - |
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
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| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
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{{author.size}} |
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