| Type | Description |
|---|---|
| Definition | selenoprotein H |
| Date | Results | Publications |
|---|---|---|
| 2018-01-27 12:08:00 | Transcriptome analysis revealed that SepH deficiency induces an inflammatory response and activates the p53 pathway. Consequently, loss of seph renders larvae susceptible to oxidative stress and DNA damage. Finally, we demonstrate that seph interacts with p53 deficiency in adulthood to accelerate gastrointestinal tumor development | 27588899 |
| Type | IDs |
|---|---|
| Synonymous | cb697, selh, seph, wu:fa11g07, wu:fb23d03 |
| Gene | |
| Nucleutide sequences | |
| Protein sequencees |
RefSeq:
NP_835234.2
|
| Others |
UniGene:
Dr.361
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 30837464 |
Nat Commun D Zada , I Bronshtein , T Lerer-Goldshtein , Y Garini , L Appelbaum |
2019-03-05 | - |
| 27588899 |
Proc. Natl. Acad. Sci. U.S.A. Andrew G Cox , Allison Tsomides , Andrew J Kim , Diane Saunders , Katie L Hwang , Kimberley J Evason , Jerry Heidel , Kristin K Brown , Min Yuan , Evan C Lien , Byung Cheon Lee , Sahar Nissim , Bryan Dickinson , Sagar Chhangawala , Christopher J Chang , John M Asara , Yariv Houvras , Vadim N Gladyshev , Wolfram Goessling |
2016-09-20 | - |
| 25064324 |
Selenium prevents downregulation of antioxidant selenoprotein genes by methylmercury. Free Radic. Biol. Med. S Penglase , K Hamre , S Ellingsen |
2014-10-01 |
msrb1b,
fep15,
fam213aa,
seph,
selm,
sepn1,
sepw1,
msrb1a,
selt2,
selt1a,
selt1b,
sep15,
txnrd1,
txnrd3,
gpx1a,
gpx4a,
gpx4b,
sepp1a,
sps2,
dio2,
sepw2a,
sepw2b,
gpx1b,
trnau1apa,
selo,
rpl13a,
selj,
uba52,
trnau1apb,
sepp1b,
selk,
si:ch1073-179p4.3,
gpx3,
dio1
|
| 22479358 |
Composition and evolution of the vertebrate and mammalian selenoproteomes. PLoS ONE Marco Mariotti , Perry G Ridge , Yan Zhang , Alexei V Lobanov , Thomas H Pringle , Roderic Guigo , Dolph L Hatfield , Vadim N Gladyshev |
2012-01-01 |
VIMP
|
| 21873635 |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas |
2011-09-01 | - |
| 15256591 |
Identification of 315 genes essential for early zebrafish development. Proc. Natl. Acad. Sci. U.S.A. Adam Amsterdam , Robert M Nissen , Zhaoxia Sun , Eric C Swindell , Sarah Farrington , Nancy Hopkins |
2004-08-31 | - |
| 12915322 |
Spatial and temporal expression patterns of selenoprotein genes during embryogenesis in zebrafish. Gene Expr. Patterns Christine Thisse , Agnès Degrave , Gregory V Kryukov , Vadim N Gladyshev , Sophie Obrecht-Pflumio , Alain Krol , Bernard Thisse , Alain Lescure |
2003-08-01 | - |
| 12775843 |
Characterization of mammalian selenoproteomes. Science Gregory V Kryukov , Sergi Castellano , Sergey V Novoselov , Alexey V Lobanov , Omid Zehtab , Roderic Guigó , Vadim N Gladyshev |
2003-05-30 |
Vimp,
Dio1,
Selo,
BC089491,
2700094K13Rik,
Gpx6,
Selk,
Dio1,
Gpx6,
Vimp,
Selk,
Selo,
RGD1563348,
seph,
C11orf31,
SEPW1,
C14H11orf31,
DIO2,
DIO1,
SEPW1,
TXNRD3,
DIO1,
GPX6,
C11orf31,
SELV,
SELT,
VIMP,
SELK,
SEPW1,
SELO,
EPT1,
GPX6,
C15H11orf31,
DIO1
|
| 12477932 |
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc. Natl. Acad. Sci. U.S.A. Robert L Strausberg , Elise A Feingold , Lynette H Grouse , Jeffery G Derge , Richard D Klausner , Francis S Collins , Lukas Wagner , Carolyn M Shenmen , Gregory D Schuler , Stephen F Altschul , Barry Zeeberg , Kenneth H Buetow , Carl F Schaefer , Narayan K Bhat , Ralph F Hopkins , Heather Jordan , Troy Moore , Steve I Max , Jun Wang , Florence Hsieh , Luda Diatchenko , Kate Marusina , Andrew A Farmer , Gerald M Rubin , Ling Hong , Mark Stapleton , M Bento Soares , Maria F Bonaldo , Tom L Casavant , Todd E Scheetz , Michael J Brownstein , Ted B Usdin , Shiraki Toshiyuki , Piero Carninci , Christa Prange , Sam S Raha , Naomi A Loquellano , Garrick J Peters , Rick D Abramson , Sara J Mullahy , Stephanie A Bosak , Paul J McEwan , Kevin J McKernan , Joel A Malek , Preethi H Gunaratne , Stephen Richards , Kim C Worley , Sarah Hale , Angela M Garcia , Laura J Gay , Stephen W Hulyk , Debbie K Villalon , Donna M Muzny , Erica J Sodergren , Xiuhua Lu , Richard A Gibbs , Jessica Fahey , Erin Helton , Mark Ketteman , Anuradha Madan , Stephanie Rodrigues , Amy Sanchez , Michelle Whiting , Anup Madan , Alice C Young , Yuriy Shevchenko , Gerard G Bouffard , Robert W Blakesley , Jeffrey W Touchman , Eric D Green , Mark C Dickson , Alex C Rodriguez , Jane Grimwood , Jeremy Schmutz , Richard M Myers , Yaron S N Butterfield , Martin I Krzywinski , Ursula Skalska , Duane E Smailus , Angelique Schnerch , Jacqueline E Schein , Steven J M Jones , Marco A Marra , Mammalian Gene Collection Program Team |
2002-12-24 | - |
| 排名 | 科研单位 | 文献 |
|---|---|---|
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