| Type | Description |
|---|---|
| Definition | leucine rich repeat transmembrane neuronal 3 |
| Date | Results | Publications |
|---|---|---|
| 2014-12-06 12:21:00 | LRRTM3 polymorphisms may play a role in the pathogenesis of late-onset Alzheimer's disease (LOAD) in a Northern Han Chinese population. | 24463050 |
| 2014-10-04 12:08:00 | protein interactions between LRRTM3, APP and BACE1, as well as complex associations between mRNA levels of LRRTM3, CTNNA3, APP and BACE1 in humans might influence APP metabolism and ultimately risk of AD | 23750206 |
| 2013-07-13 13:17:00 | LRRTM3 is not an essential regulator of amyloid-beta production in adult mice; there are no differences in genotype between levels of Abeta or Abeta protein precursor C-terminal fragments in vivo. | 22710909 |
| 2012-11-24 10:14:00 | One single-nucleotide polymorphism in the promoter region and a block of 4 single-nucleotide polymorphisms in intron 2 were associated with AD in the National Institute on Aging Late-Onset Alzheimer's Disease data set or the Caribbean Hispanic data set. | 22393166 |
| 2011-09-10 12:10:00 | Apart from the complexity of its regulation, alterations in both CTNNA3 and LRTMM3 are implicated in human disease. | 21598020 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
LRRT3_HUMAN
UniprotKB:
Q86VH5
UniParc:
UPI0000088C0F,
UPI00000389FF
EMBL:
BX640611,
BC113715,
AY182028,
AK290168,
BC113717,
BC111492,
AY358315
Ensembl:
ENSG00000198739
KO:
hsa:347731
|
| Nucleutide sequences |
EMBL-CDS:
BAF82857.1,
AAI11493.1,
CAE45717.1,
AAI13718.1,
AAO67549.1,
AAQ88681.1,
AAI13716.1
Gene_ORFName:
UNQ803/PRO1693
Ensembl_TRS:
ENST00000361320
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000355187
RefSeq:
NP_821079.3
|
| Others |
UniRef100:
UniRef100_Q86VH5
UniRef90:
UniRef90_Q86VH5
UniRef50:
UniRef50_Q86VH5
UniGene:
Hs.652155
CCDS:
CCDS7270.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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