| Type | Description |
|---|---|
| Definition | loquacious |
| Date | Results | Publications |
|---|---|---|
| 2019-07-20 11:06:00 | We also found that a base-mismatch can enable Loqs-PB to tune miRNA length. We speculate that Loqs-PB tunes miRNA length by changing the conformation of base-mismatched nucleotides in the pre-miRNA stem to that of base-matched ones. | 29373753 |
| 2018-06-09 12:20:00 | studies indicate that the 22 amino acids at the C terminus of Loqs-PD, including an FDF-like motif, directly interact with the Hel2 subdomain of Dicer-2's helicase domain. This interaction is RNA-independent, but we find that modulation of Dicer-2 cleavage also requires dsRNA binding by Loqs-PD. | 28874570 |
| 2018-04-14 10:36:00 | Loqs-PD removes the inhibitory effect of inorganic phosphate on Dicer-2 processing of blunt-end hairpin RNAs, allowing siRNA production in the presence of inorganic phosphate. | 29550490 |
| 2017-12-30 11:49:00 | binding preference for the thermodynamically more stable siRNA end by Loqs-PD alone is greatly amplified in complex with Dcr-2 to initiate strand discrimination by asymmetry sensing in the RISC loading complex. | 29040648 |
| 2017-11-18 10:48:00 | Loqs may have roles in assisting the de novo emergence of miRNA genes by facilitating dicing of suboptimal hairpin substrates. | 27184838 |
| Type | IDs |
|---|---|
| Synonymous | CG6866, Dmel\CG6866, LOQS, Loqs, R3D1, R3D1-L, R3D1-S, TRBP, cg6866, dRax, loq, r3d1 |
| Gene |
UniProtKB-ID:
Q8IP72_DROME,
Q9VJY9_DROME,
Q4TZM6_DROME,
X2J5X6_DROME,
X2JAB1_DROME,
M9MRT5_DROME
UniprotKB:
Q8IP72,
Q9VJY9,
Q4TZM6,
X2J5X6,
X2JAB1,
M9MRT5
UniParc:
UPI00032D687C,
UPI0001F770CA,
UPI000008472A,
UPI0000519429,
UPI00032D68B6,
UPI00000779A7
EMBL:
DQ026059,
DQ118035,
AE014134,
AY071070,
DQ118034
EnsemblGenome:
FBgn0032515
KO:
dme:Dmel_CG6866
|
| Nucleutide sequences |
EMBL-CDS:
AAZ40192.1,
AAF53296.1,
AAL48692.1,
AAF53295.2,
AAZ40191.1,
ABC65897.1,
AAY40789.1,
AHN54408.1,
AHN54407.1,
ADV37046.1
Gene_ORFName:
Dmel_CG6866,
CG6866,
Dmel_CG6866,
CG6866,
CG6866,
Dmel_CG6866,
Dmel_CG6866,
CG6866,
CG6866,
Dmel_CG6866,
CG6866,
Dmel_CG6866
EnsemblGenome_TRS:
FBtr0080497,
FBtr0080498,
FBtr0100220,
FBtr0342633,
FBtr0342632,
FBtr0303269
|
| Protein sequencees |
EnsemblGenome_PRO:
FBpp0080075,
FBpp0080076,
FBpp0099590,
FBpp0309562,
FBpp0309561,
FBpp0292361
RefSeq:
NP_001033903.1,
NP_723813.1,
NP_001285893.1,
NP_609646.1,
NP_001188796.1,
NP_001285894.1
|
| Others |
UniRef100:
UniRef100_Q4TZM6,
UniRef100_X2JAB1,
UniRef100_X2J5X6,
UniRef100_Q9VJY9,
UniRef100_M9MRT5,
UniRef100_Q8IP72
UniRef90:
UniRef90_Q4TZM6,
UniRef90_X2J5X6,
UniRef90_Q9VJY9
UniRef50:
UniRef50_Q9VJY9,
UniRef50_Q4TZM6
UniGene:
Dm.421
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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