Type | Description |
---|---|
Definition | apolipoprotein C4 |
Date | Results | Publications |
---|---|---|
2016-04-02 10:12:00 | APOC4 rs1132899 polymorphism was associated with an increased risk of premature coronary artery disease in Chinese subjects. | 26129832 |
2011-12-10 12:05:00 | variants in LPL, OASL and TOMM40/APOE-C1-C2-C4 genes are associated with multiple cardiovascular-related traits | 21943158 |
2011-03-07 13:06:00 | Includes the observation of APOC4-APOC2 read-through transcription | 8530039 |
2011-01-01 11:34:00 | This study examines the association between APOE/C1/C4/C2 gene cluster variation using tagging single nucleotide polymorphisms and plasma lipid concentration along with risk of coronary heart disease in a prospective cohort. | 20498921 |
2010-12-05 22:08:00 | Observational study, meta-analysis, and genome-wide association study of gene-disease association. (HuGE Navigator) | 20864672 |
Type | IDs |
---|---|
Synonymous | APO-CIV, APOC-IV |
Gene |
UniProtKB-ID:
APOC4_HUMAN
UniprotKB:
P55056
UniParc:
UPI0000125C2A
EMBL:
AY422953,
U32576,
BC020723,
CH471126,
AK126257
Ensembl:
ENSG00000267467
KO:
hsa:346
|
Nucleutide sequences |
EMBL-CDS:
AAQ91812.1,
EAW57310.1,
AAH20723.1,
AAA91653.1,
BAG54298.1
Ensembl_TRS:
ENST00000592954
|
Protein sequencees |
Ensembl_PRO:
ENSP00000468236
RefSeq:
NP_001637.1
|
Others |
UniRef100:
UniRef100_P55056
UniRef90:
UniRef90_P55056
UniRef50:
UniRef50_P55056
UniGene:
Hs.731599
CCDS:
CCDS12649.1
|
{{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
---|---|---|---|---|---|---|---|---|
Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
暂无数据
Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
---|---|---|---|
32296183 |
A reference map of the human binary protein interactome. Nature Katja Luck , Dae-Kyum Kim , Luke Lambourne , Kerstin Spirohn , Bridget E Begg , Wenting Bian , Ruth Brignall , Tiziana Cafarelli , Francisco J Campos-Laborie , Benoit Charloteaux , Dongsic Choi , Atina G Coté , Meaghan Daley , Steven Deimling , Alice Desbuleux , Amélie Dricot , Marinella Gebbia , Madeleine F Hardy , Nishka Kishore , Jennifer J Knapp , István A Kovács , Irma Lemmens , Miles W Mee , Joseph C Mellor , Carl Pollis , Carles Pons , Aaron D Richardson , Sadie Schlabach , Bridget Teeking , Anupama Yadav , Mariana Babor , Dawit Balcha , Omer Basha , Christian Bowman-Colin , Suet-Feung Chin , Soon Gang Choi , Claudia Colabella , Georges Coppin , Cassandra D'Amata , David De Ridder , Steffi De Rouck , Miquel Duran-Frigola , Hanane Ennajdaoui , Florian Goebels , Liana Goehring , Anjali Gopal , Ghazal Haddad , Elodie Hatchi , Mohamed Helmy , Yves Jacob , Yoseph Kassa , Serena Landini , Roujia Li , Natascha van Lieshout , Andrew MacWilliams , Dylan Markey , Joseph N Paulson , Sudharshan Rangarajan , John Rasla , Ashyad Rayhan , Thomas Rolland , Adriana San-Miguel , Yun Shen , Dayag Sheykhkarimli , Gloria M Sheynkman , Eyal Simonovsky , Murat TaÅan , Alexander Tejeda , Vincent Tropepe , Jean-Claude Twizere , Yang Wang , Robert J Weatheritt , Jochen Weile , Yu Xia , Xinping Yang , Esti Yeger-Lotem , Quan Zhong , Patrick Aloy , Gary D Bader , Javier De Las Rivas , Suzanne Gaudet , Tong Hao , Janusz Rak , Jan Tavernier , David E Hill , Marc Vidal , Frederick P Roth , Michael A Calderwood |
2020-04-01 | - |
26129832 |
Lipids Health Dis Shun Xu , Jie Cheng , Nan-hong Li , Yu-ning Chen , Meng-yun Cai , Sai-sai Tang , Haijiao Huang , Bing Zhang , Jin-ming Cen , Xi-li Yang , Can Chen , Xinguang Liu , Xing-dong Xiong |
2015-01-01 |
APOC4
|
25378659 |
Genetic loci associated with circulating levels of very long-chain saturated fatty acids. J Lipid Res Rozenn N Lemaitre , Irena B King , Edmond K Kabagambe , Jason H Y Wu , Barbara McKnight , Ani Manichaikul , Weihua Guan , Qi Sun , Daniel I Chasman , Millennia Foy , Lu Wang , Jingwen Zhu , David S Siscovick , Michael Y Tsai , Donna K Arnett , Bruce M Psaty , Luc Djousse , Yii-Der I Chen , Weihong Tang , Lu-Chen Weng , Hongyu Wu , Majken K Jensen , Audrey Y Chu , David R Jacobs , Stephen S Rich , Dariush Mozaffarian , Lyn Steffen , Eric B Rimm , Frank B Hu , Paul M Ridker , Myriam Fornage , Yechiel Friedlander |
2015-01-01 | - |
21873635 |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas |
2011-09-01 | - |
21103663 |
Identification of VKORC1 interaction partners by split-ubiquitin system and coimmunoprecipitation. Thromb. Haemost. Anne Schaafhausen , Simone Rost , Johannes Oldenburg , Clemens R Müller |
2011-02-01 |
HDAC6,
TMEM35B,
PDIA6,
BCAP31,
ATP6AP2,
IFITM3,
PROCR,
ARL6IP5,
EBP,
YIF1A,
TREX1,
TMEM45B,
CNN3,
COMT,
SLC31A2,
CCDC12,
CXADR,
CCDC167,
VKORC1L1,
SPTSSA,
METTL7B,
AHSG,
ZCCHC24,
FGG,
FGL1,
TRAM1,
FTL,
TMEM256,
GJB1,
PPA2,
SERP1,
TMEM230,
HP,
HPR,
APLP2,
APOA1,
APOA2,
APOC1,
APOC3,
APOC4,
ASGR1,
ASGR2,
MT1X,
PCDH1,
FIS1,
PCMT1,
RMDN1,
SLC15A3,
HSD17B7,
TMBIM4,
MSRB1,
ATP5G3,
SERPINA1,
PIGH,
PLP2,
PPIB,
TMEM176A,
ECHDC1,
HAMP,
SAA1,
SAT1,
MSMO1,
RMND5A,
SLC25A1,
SNORA12,
STAT6,
SURF4,
TF,
C1S,
TMEM242,
VKORC1,
REEP5,
TMEM134,
TMEM120A,
JAGN1,
DPM2,
KCNK17,
CLDN10,
VAPB,
CD9,
HOMER2,
CD63,
CD81
|
21943158 |
BMC Med. Genet. Rita P S Middelberg , Manuel A R Ferreira , Anjali K Henders , Andrew C Heath , Pamela A F Madden , Grant W Montgomery , Nicholas G Martin , John B Whitfield |
2011-01-01 |
SLC17A4,
LOC102724766,
TOMM40,
CETP,
CELSR2,
GCKR,
HFE,
APOB,
APOC1,
APOC2,
APOC4,
APOE,
LDLR,
LIPC,
LPL,
MRC1,
BCHE,
TAGLN,
OASL,
PCSK7,
ABCG2,
WDR1
|
20972250 |
J. Med. Genet. Mi-Hyun Park , NamHee Kim , Jong-Young Lee , Hyun-Young Park |
2011-01-01 |
TRIB1,
ACAA2,
TTC39B,
ABCA1,
PCSK9,
TBL2,
HAVCR1,
ANGPTL3,
XKR6,
HMGCR,
MMAB,
APOB,
APOC1,
APOC2,
APOC4,
APOE,
LCAT,
LDLR,
FADS1,
FADS3,
MVK,
MLXIPL,
PLTP,
SLC35G5,
DOCK7,
TIMD4,
BCL7B,
LIPG,
FADS2
|
20855565 |
J Lipid Res Gina M Peloso , Serkalem Demissie , Dorothea Collins , Daniel B Mirel , Stacey B Gabriel , L Adrienne Cupples , Sander J Robins , Ernst J Schaefer , Margaret E Brousseau |
2010-12-01 | - |
20864672 |
Genetic variants influencing circulating lipid levels and risk of coronary artery disease. Arterioscler. Thromb. Vasc. Biol. Dawn M Waterworth , Sally L Ricketts , Kijoung Song , Li Chen , Jing Hua Zhao , Samuli Ripatti , Yurii S Aulchenko , Weihua Zhang , Xin Yuan , Noha Lim , Jian'an Luan , Sofie Ashford , Eleanor Wheeler , Elizabeth H Young , David Hadley , John R Thompson , Peter S Braund , Toby Johnson , Maksim Struchalin , Ida Surakka , Robert Luben , Kay-Tee Khaw , Sheila A Rodwell , Ruth J F Loos , S Matthijs Boekholdt , Michael Inouye , Panagiotis Deloukas , Paul Elliott , David Schlessinger , Serena Sanna , Angelo Scuteri , Anne Jackson , Karen L Mohlke , Jaako Tuomilehto , Robert Roberts , Alexandre Stewart , Y Antero Kesäniemi , Robert W Mahley , Scott M Grundy , Wellcome Trust Case Control Consortium , Wendy McArdle , Lon Cardon , Gérard Waeber , Peter Vollenweider , John C Chambers , Michael Boehnke , Gonçalo R Abecasis , Veikko Salomaa , Marjo-Riitta Järvelin , Aimo Ruokonen , Inês Barroso , Stephen E Epstein , Hakon H Hakonarson , Daniel J Rader , Muredach P Reilly , Jacqueline C M Witteman , Alistair S Hall , Nilesh J Samani , David P Strachan , Philip Barter , Cornelia M van Duijn , Jaspal S Kooner , Leena Peltonen , Nicholas J Wareham , Ruth McPherson , Vincent Mooser , Manjinder S Sandhu |
2010-11-01 | - |
20628086 |
Diabetes Care Swneke D Bailey , Changchun Xie , Ron Do , Alexandre Montpetit , Rafael Diaz , Viswanathan Mohan , Bernard Keavney , Salim Yusuf , Hertzel C Gerstein , James C Engert , Sonia Anand , DREAM investigators |
2010-10-01 | - |
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