| Type | Description |
|---|---|
| Definition | solute carrier family 10 member 6 |
| Date | Results | Publications |
|---|---|---|
| 2019-03-30 11:55:00 | SOAT genetic variants L44P, Q75R, P107L, G109S, S112F, N113K, S133F, G241D, G263E, G294R, and Y308N showed no transport activity for dehydroepiandrosterone sulfate at all. In the case of P107L, G241D, G263E, and Y308N, this was most likely due to significantly reduced expression in the plasma membrane. | 28893621 |
| 2019-03-30 10:19:00 | SOAT substrates from the group of sulfated steroids are characterized by a planar and lipophilic steroid backbone in trans-trans-trans conformation of the rings and a negatively charged mono-sulfate group at positions 3' or 17' with flexibility for alpha- or beta- orientation. Furthermore, 5alpha-reduction, 16alpha-hydroxylation, and 17alpha-hydroxylation are acceptable for SOAT substrate recognition, whereas addition ... | 28951227 |
| 2019-03-30 10:19:00 | SOAT-L204F polymorphism was found in men with normal spermatogenesis and with hypospermatogenesisSOAT-L204F polymorphism showed impaired membrane expression.The SOAT-L204F polymorphism showed reduced transport activity for dehydroepiandrosterone sulfate. | 28951225 |
| Type | IDs |
|---|---|
| Synonymous | SOAT |
| Gene |
UniProtKB-ID:
SOAT_HUMAN
UniprotKB:
Q3KNW5
UniParc:
UPI00001977FD
EMBL:
BC107051,
BC107052,
EF437223,
AJ583502,
CH471057
Ensembl:
ENSG00000145283
KO:
hsa:345274
|
| Nucleutide sequences |
EMBL-CDS:
CAE47477.1,
AAI07053.1,
AAI07052.1,
ABO38126.1,
EAX05969.1
Ensembl_TRS:
ENST00000273905
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000273905
RefSeq:
NP_932069.1
|
| Others |
UniRef100:
UniRef100_Q3KNW5
UniRef90:
UniRef90_Q3KNW5
UniRef50:
UniRef50_Q3KNW5
UniGene:
Hs.452996
CCDS:
CCDS3614.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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