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34413 da

34413

da

daughterless

protein-coding

Drosophila melanogaster

基因描述

Type Description
Definition daughterless

研究结论

Date Results Publications
2020-05-16 10:38:00 provides initial insights into the mechanisms underlying the function of daughterless and Emc in neurons while providing a novel understanding of how Emc functions to restrict daughterless activity within the cell 31581354
2019-06-01 12:43:00 Daughterless level sets Emc protein levels in most cells, apparently by stabilizing Emc in heterodimers. Emc is destabilized in proneural regions by local competition for heterodimer formation by proneural bHLH proteins including Atonal or AS-C proteins. 29687780
2019-04-20 11:59:00 Suppression of da by wild-type emc was essential for cell chirality formation and for normal left-right asymmetric development of the embryonic hindgut. 30624823
2016-12-31 10:37:00 Daughterless and Tcf4 are expressed in postmitotic neurons in Drosophila melanogaster and mice, respectively, where they function to restrict neurite branching and synapse formation in part by restricting the expression of the cell adhesion molecule Neurexin. 27050508
2015-08-15 10:23:00 Notch signaling activates the expression of extramacrochaetae (emc), which encodes a helix-loop-helix (HLH) transcription factor. Emc, in turn, then forms a biochemical complex with Da. 25977368

名称对应

Type IDs
Synonymous 5102, CG5102, DA, Da, Dmel\CG5102, SC_DA, bHLHb22, l(2)31Ea, l(2)k08611
Gene
UniProtKB-ID: DA_DROME, C8VV95_DROME
UniprotKB: P11420, C8VV95
UniParc: UPI000000748B
EMBL: BT128758, AE014134, BT099841, J03148, Y00221
EnsemblGenome: FBgn0267821
KO: dme:Dmel_CG5102
Nucleutide sequences
EMBL-CDS: CAA68368.1, AAF52934.2, AAA28442.1, AEI73809.1, AGB92876.1, AGB92875.1, ACW83549.1
Gene_ORFName: CG5102, CG5102, Dmel_CG5102
EnsemblGenome_TRS: FBtr0332196, FBtr0080008, FBtr0332195, FBtr0332195, FBtr0080008, FBtr0332196
Protein sequencees
EnsemblGenome_PRO: FBpp0304504, FBpp0079598, FBpp0304505, FBpp0079598, FBpp0304504, FBpp0304505
RefSeq: NP_001356956.1, NP_477189.1, NP_001260340.1, NP_001260341.1
Others
UniRef100: UniRef100_P11420
UniRef90: UniRef90_P11420
UniRef50: UniRef50_P11420
UniGene: Dm.388

全选

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