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34411 Cdk1

34411

Cdk1

Cyclin-dependent kinase 1

protein-coding

Drosophila melanogaster

基因描述

Type Description
Definition Cyclin-dependent kinase 1

研究结论

Date Results Publications
2021-01-09 13:33:00 Cyclin B3 activates the Anaphase-Promoting Complex/Cyclosome in meiosis and mitosis. 33137813
2020-02-22 11:58:00 Cyclin B1-Cdk1 localized at the spindle midzone in an Aurora B-dependent manner, with incompletely separated chromosomes showing the highest Cdk1 activity. Slowing down anaphase chromosome motion delayed Cyclin B1 degradation and mitotic exit in an Aurora B-dependent manner. 31424385
2018-03-24 10:13:00 Physical interaction between p115 and Cdk1, suggests that p115 sequesters or re-localizes Cdk1 during mitosis to allow the complete activation of Cdk1 and consequently correct progression through mitosis in Drosophila imaginal cells. 28396045
2018-02-24 11:12:00 Here the authors show that CDK1 phosphorylation of GNU negatively regulates PNG kinase activity. 28555567
2017-07-01 12:33:00 Cdk1 waves are not controlled by the mitotic switch but by a double-negative feedback between Cdk1 and Chk1. In Drosophila embryos, Cdk1 positive feedback serves primarily to ensure the rapid onset of mitosis, while wave propagation is regulated by S phase events. 27554859

名称对应

Type IDs
Synonymous 5363, CDC2, CDCDm, CDK1, CDK1/CDC2, CG5363, Cdc2, Cdk-1, Dcdc2, Dm cdc2, DmCdc2, DmCdk1, Dmcdc2, Dmel\CG5363, cdc, cdc2, cdc2Dm, cdk1, dCdk1, group 4, l(2)31Eh
Gene
UniProtKB-ID: CDK1_DROME, C0MJ66_DROME
UniprotKB: P23572, C0MJ66
UniParc: UPI0000000E63
EMBL: FM245388, FM245391, FM245393, AM294321, FM245389, X57485, FM245394, AM294329, FM245397, S66801, S66805, FM245392, S66810, AM294322, AM294327, AM294320, FM245396, AE014134, FM245390, AM294324, X57496, S66807, AM294323, AM294328, S66804, FM245395, AM294326, AM294325, AM294319, AY061450, FM245398
EnsemblGenome: FBgn0004106
KO: dme:Dmel_CG5363
Nucleutide sequences
EMBL-CDS: CAL26249.1, CAL26259.1, CAL26252.1, CAL26253.1, CAA40733.1, AAP13986.1, AAP13988.1, CAL26250.1, AAP13989.1, CAL26254.1, CAL26258.1, CAA40723.1, CAL26251.1, CAL26256.1, AAP13987.1, CAL26255.1, AAP13990.1, CAL26257.1, AAL28998.1, AAF52932.1, CAR93316.1, CAR93321.1, CAR93318.1, CAR93319.1, CAR93320.1, CAR93323.1, CAR93315.1, CAR93314.1, CAR93317.1, CAR93324.1, CAR93322.1
Gene_ORFName: CG5363
EnsemblGenome_TRS: FBtr0080051, FBtr0080051
Protein sequencees
EnsemblGenome_PRO: FBpp0079641, FBpp0079641
RefSeq: NP_476797.1
Others
UniRef100: UniRef100_P23572
UniRef90: UniRef90_P23572
UniRef50: UniRef50_P23572
UniGene: Dm.3187

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