| Type | Description |
|---|---|
| Definition | interferon, type 1, cluster |
| Date | Results | Publications |
|---|---|---|
| 2018-05-12 10:53:00 | By fusing the MCF-7 binding peptide (MBP) to the C-terminus of IFNalpha, we constructed an engineered IFNalpha-MBP fusion molecule (IMBP), and applied this novel fusion protein to the treatment of breast cancer. We found that IMBP exhibited significantly higher activity than wild-type IFNalpha in inhibiting cell growth and inducing cell apoptosis | 28677808 |
| 2013-11-16 11:12:00 | These data suggest that type I IFN stimulation induces a rapid recruitment of a repressive Egr3/Nab1 complex that silences transcription from the ifngr1 promoter. | 23935197 |
| 2013-03-30 11:29:00 | monocytes manage the impact of TNF-alpha and type I/II interferons in rheumatoid arthritis and systemic lupus erythematosus | 22610275 |
| 2012-09-01 11:02:00 | NS1 binds to MAVS and this binding inhibits the MAVS-RIG-I interaction required for IFN production | 22383950 |
| 2011-12-10 10:52:00 | IFN-alpha increased the percentage of lymphocytes staining positive for intracellular phosphorylated p38. IFNA-induced increases in p-p38 were significantly greater in patients that developed clinically significant depressive symptoms. | 21356304 |
| Type | IDs |
|---|---|
| Synonymous | IFNA |