| Type | Description |
|---|---|
| Definition | interferon induced protein with tetratricopeptide repeats 3 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-13 13:24:00 | Novel evidence for retinoic acid-induced G (Rig-G) as a tumor suppressor by activating p53 signaling pathway in lung cancer. | 32741018 |
| 2019-10-05 13:09:00 | ISG60 constitutes a negative feedback loop in the downstream of TLR3 signaling in brain capillary endothelial cells. | 30195920 |
| 2019-08-24 12:26:00 | IFIT1 and IFIT3 interact through a C-terminal motif. IFIT3 stabilizes IFIT1 protein expression, promotes IFIT1 binding to a cap0 Zika virus reporter mRNA and enhances IFIT1 translation inhibition. | 29554348 |
| 2019-08-03 10:07:00 | Levels of IFIT3 were significantly elevated in human systemic lupus erythematosus monocytes, and this was positively correlated with the activity of the cGAS/STING signaling pathway. In vitro, the expression of VACV70-induced IFNbeta was reduced by knockdown of IFIT3, whereas overexpression of IFIT3 produced an opposite effect. Finally, IFIT3 was found to interact with both STING and TANK-binding kinase 1. | 29806091 |
| 2019-05-25 12:06:00 | A statistically positive correlation of p-EGFR(Y1068) expression with IFIT1 and IFIT3 in OSCC tumors. | 30626937 |
| Type | IDs |
|---|---|
| Synonymous | CIG-49, GARG-49, IFI60, IFIT4, IRG2, ISG60, P60, RIG-G, cig41 |
| Gene |
UniProtKB-ID:
IFIT3_HUMAN,
Q5T765_HUMAN
UniprotKB:
O14879,
Q5T765
UniParc:
UPI000012D3E5
EMBL:
AK290427,
AF026939,
BC001383,
AF083470,
U52513,
BT007284,
CH471066,
BC004977
Ensembl:
ENSG00000119917
KO:
hsa:3437
|
| Nucleutide sequences |
EMBL-CDS:
AAH01383.1,
AAH04977.1,
AAB95160.1,
AAP35948.1,
AAC63524.1,
AAB40606.1,
EAW50143.1,
BAF83116.1,
EAW50144.1
Gene_ORFName:
hCG_24570
Ensembl_TRS:
ENST00000371818,
ENST00000371811
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000360876,
ENSP00000360883
RefSeq:
NP_001026853.1,
NP_001540.2,
NP_001276688.1,
NP_001276687.1
|
| Others |
UniRef100:
UniRef100_O14879
UniRef90:
UniRef90_O14879
UniRef50:
UniRef50_O14879
UniGene:
Hs.744072
CCDS:
CCDS31241.1,
CCDS7402.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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