| Type | Description |
|---|---|
| Definition | potassium sodium-activated channel subfamily T member 2 |
| Date | Results | Publications |
|---|---|---|
| 2021-01-16 15:55:00 | In silico and in vitro analysis of cation-activated potassium channels in human corneal endothelial cells. | 32561484 |
| 2020-09-12 16:03:00 | An inducible circular RNA circKcnt2 inhibits ILC3 activation to facilitate colitis resolution. | 32796851 |
| 2020-03-21 11:52:00 | The expression of three genes (STK26, KCNT2, CASP12) was correlated with the prognosis of skin cutaneous melanoma (SCM). STK26 and KCNT2 were significantly different between normal skin and SCM. These three hub genes have potential value as predictors for accurate diagnosis and prognosis of SCM in the future. | 31557882 |
| 2018-06-16 12:11:00 | Pathogenic Phe240Leu mutation in KCNT2 channel changes ion selectivity. | 29069600 |
| 2017-09-23 13:54:00 | In the present study, we evaluated two other potential mechanisms for stabilization of Slo2 channels in a closed state: (1) dewetting and collapse of the inner pore (hydrophobic gating) and (2) constriction of the inner pore by tight criss-crossing of the cytoplasmic ends of the S6 alpha-helical segments. | 27682982 |
| Type | IDs |
|---|---|
| Synonymous | EIEE57, KCa4.2, SLICK, SLO2.1 |
| Gene |
UniProtKB-ID:
KCNT2_HUMAN,
A0A3B3IRL4_HUMAN,
A9LNM6_HUMAN
UniprotKB:
Q6UVM3,
A0A3B3IRL4,
A9LNM6
UniParc:
UPI000035E80D,
UPI00001E0966,
UPI000022AF13,
UPI0000E05FC1,
UPI00005B728C
EMBL:
BX647852,
AL138931,
AL358853,
AK131498,
BC103949,
EU251076,
AL139137,
AY359444,
BC103950,
AL591604,
BC103948
Ensembl:
ENSG00000162687
KO:
hsa:343450
|
| Nucleutide sequences |
EMBL-CDS:
AAI03949.1,
BAD18642.1,
AAI03950.1,
AAI03951.1,
CAI46099.1,
AAR06170.1,
ABX11496.1
Ensembl_TRS:
ENST00000294725,
ENST00000367433,
ENST00000609185,
ENST00000647658
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000356403,
ENSP00000476657,
ENSP00000294725,
ENSP00000496885
RefSeq:
XP_024302465.1,
XP_006711357.1,
NP_001274749.1,
XP_006711358.1,
XP_016856674.1,
XP_016856668.1,
XP_016856672.1,
XP_011507785.1,
XP_016856670.1,
NP_940905.2,
NP_001274748.1,
XP_016856669.1
|
| Others |
UniRef100:
UniRef100_Q6UVM3,
UniRef100_A0A3B3IRL4
UniRef90:
UniRef90_A0A3B3IRL4,
UniRef90_Q6UVM3
UniRef50:
UniRef50_Q5JUK3-2,
UniRef50_A0A3B3IRL4
UniGene:
Hs.657046
CCDS:
CCDS72995.1,
CCDS1384.1,
CCDS72994.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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