Type | Description |
---|---|
Definition | olfactory receptor family 2 subfamily W member 3 |
Date | Results | Publications |
---|---|---|
2021-01-09 13:33:00 | The odorant receptor OR2W3 on airway smooth muscle evokes bronchodilation via a cooperative chemosensory tradeoff between TMEM16A and CFTR. | 33097666 |
2018-01-20 10:15:00 | A signal in a nearby olfactory receptor on chromosome 1, olfactory receptor family 2 subfamily L member 13 (OR2L13), tagged by rs151319968, was nominally associated with PTSD in the AI sample. Although no variants were significantly associated after correction for multiple testing in a meta-analysis of the two cohorts, pathway analysis of the top hits showed an enrichment cluster of terms related to sensory transduction. | 28262088 |
2017-11-11 11:59:00 | We therefore conclude that this sequence variant, and hence the OR2W3 gene, do not cause RP. Prompted by these findings and based on simple principles of population genetics, we suggest that WES studies should consider DNA variants as the possible cause of dominant RP only if they are present in less than 1:100,000 individuals from the general population. | 26891008 |
2017-08-19 11:13:00 | This outstanding specificity of extremely narrowly tuned human OR2M3 can explain both odor qualities and odor threshold trend within a homologous series of 3-mercapto-2-methylalkan-1-ols and suggests a modern human-specific, food-related function of OR2M3 in detecting a single onion key food odorant. | 27916748 |
2016-05-07 10:50:00 | OR2W3 is associated with genetic susceptibility to Japanese male infertility. | 25847845 |
Type | IDs |
---|---|
Synonymous | OR2W3P, OR2W8P, OST718 |
Gene |
UniProtKB-ID:
OR2W3_HUMAN
UniprotKB:
Q7Z3T1
UniParc:
UPI0000061EA8
EMBL:
BX537432,
AB065949,
BK004456
Ensembl:
ENSG00000238243
KO:
hsa:343171
|
Nucleutide sequences |
EMBL-CDS:
CAD97674.1,
DAA04854.1,
BAC06162.1
Ensembl_TRS:
ENST00000360358
|
Protein sequencees |
Ensembl_PRO:
ENSP00000353516
RefSeq:
NP_001001957.2
|
Others |
UniRef100:
UniRef100_Q7Z3T1
UniRef90:
UniRef90_Q7Z3T1
UniRef50:
UniRef50_O76001
UniGene:
Hs.269151
CCDS:
CCDS31099.1
|
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