| Type | Description |
|---|---|
| Definition | SP110 nuclear body protein |
| Date | Results | Publications |
|---|---|---|
| 2021-02-13 13:29:00 | Novel Missense Mutation inSP110Associated with Combined Immunodeficiency and Advanced Liver Disease Without VOD. | 31721003 |
| 2019-04-27 11:01:00 | Results suggest that the SP110 variants have a role in controlling genetic susceptibility to latent and active tuberculosis (TB) infection in Taiwan. Additionally, the SP110 rs9061 SNP is shown to be associated with plasma TNFalpha levels in LTBI individuals. These data suggest that the identified SP110 SNPs may serve as a biomarker for latent and active TB infection in Taiwan. | 30627224 |
| 2018-08-18 11:22:00 | TNF-alpha -308G>A (rs1800629) showed no association with susceptibility to pulmonary tuberculosis and spinal tuberculosis patients in southern China. | 29430075 |
| 2018-02-17 10:34:00 | SP110 polymorphism is associated with tuberculosis. | 27623071 |
| 2018-01-27 10:20:00 | Data suggest that Sp110 is sumoylated, de-sumoylated, and then released from the promyelocytic leukemia nuclear bodies in hepatocytes infected with HBV (hepatitis B virus); Sp110 differentially regulates several direct target genes of HBx, a viral co-factor; these mechanisms may be involved in evasion of host immune response by HBV. (Sp110 = Speckled 110 kDa; HBx = hepatitis B virus protein X) | 29046350 |
| Type | IDs |
|---|---|
| Synonymous | IFI41, IFI75, IPR1, VODI |
| Gene |
UniProtKB-ID:
SP110_HUMAN
UniprotKB:
Q9HB58
UniParc:
UPI0001E88EDB,
UPI000013CFC9,
UPI000013CFCA,
UPI0001E88EDA,
UPI0001D411CC,
UPI000013D98F,
UPI0001E88EDC
EMBL:
AF280094,
BC019059,
L22343,
AC009950,
L22342,
AK026488,
CH471063,
AK301097,
AF280095
Ensembl:
ENSG00000135899
KO:
hsa:3431
|
| Nucleutide sequences |
EMBL-CDS:
AAF99318.1,
AAD13402.1,
EAW70915.1,
AAX93281.1,
AAA18806.1,
AAH19059.1,
BAG62696.1,
AAG09826.1
Ensembl_TRS:
ENST00000540870,
ENST00000258382,
ENST00000358662,
ENST00000258381
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000258381,
ENSP00000351488,
ENSP00000258382,
ENSP00000439558
RefSeq:
NP_001365373.1,
XP_016859457.1,
NP_004501.4,
XP_011509394.1,
NP_001365374.1,
NP_536349.3,
NP_001365376.1,
NP_001365371.1,
XP_016859458.1,
NP_001365375.1,
NP_001365372.1,
NP_001171944.1,
XP_011509392.1,
XP_011509393.1,
NP_004500.4,
XP_024308618.1
|
| Others |
UniRef100:
UniRef100_Q9HB58
UniRef90:
UniRef90_Q9HB58
UniRef50:
UniRef50_Q9HB58
UniGene:
Hs.145150
CCDS:
CCDS2474.1,
CCDS2476.1,
CCDS2475.1,
CCDS54435.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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