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3430 IFI35

3430

IFI35

interferon induced protein 35

protein-coding

Homo sapiens

基因描述

Type Description
Definition interferon induced protein 35

研究结论

Date Results Publications
2020-11-21 13:26:00 IFI35 as a biomolecular marker of neuroinflammation and treatment response in multiple sclerosis. 32781067
2019-09-21 10:17:00 inhibits both endothelial cell proliferation and migration by inhibiting the NF-kappaB/p65 pathway; functionally interacts with Nmi through its NID1 domain 29350881
2018-05-26 10:39:00 IFI35 enhances proliferation of mesangial cells and is regulated by MBD2 in lupus nephritis. 28064541
2018-02-17 10:12:00 Damage-associated molecular patterns (DAMP) are important mediators of innate immunity. Here the authors show that N-myc and interactor (NMI) and interferon-induced protein 35 (IFP35) act as DAMPs to promote inflammation by activating macrophages via the Toll-like receptor 4 and NF-kappaB pathways. 29038465
2017-08-12 11:06:00 Study found that TLR3 signaling induces the expression of IFI35, and IFI35 negatively regulates axis in U373MG cells. This suggests that IFI35 expressed in astrocytes may play an important role in regulating the innate immune system in astrocytoma cells. 28109979

名称对应

Type IDs
Synonymous IFP35
Gene
UniProtKB-ID: IN35_HUMAN
UniprotKB: P80217
UniParc: UPI0001AE674A, UPI0000200E4E
EMBL: BC001356, L78833, U72882, AC055866
Ensembl: ENSG00000068079
KO: hsa:3430
Nucleutide sequences
EMBL-CDS: AAC37597.1, AAB61703.1, AAH01356.1
Ensembl_TRS: ENST00000415816, ENST00000438323
Protein sequencees
Ensembl_PRO: ENSP00000394579, ENSP00000395590
RefSeq: NP_005524.2, NP_001317159.1, XP_016880074.1, XP_016880073.1
Others
UniRef100: UniRef100_P80217
UniRef90: UniRef90_P80217
UniRef50: UniRef50_P80217
UniGene: Hs.632258
CCDS: CCDS11450.1, CCDS82134.1

全选

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研究热度

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