| Type | Description |
|---|---|
| Definition | complement factor I |
| Date | Results | Publications |
|---|---|---|
| 2021-04-03 13:30:00 | Complement family member CFI polymorphisms and AMD susceptibility from a comprehensive analysis. | 32215612 |
| 2021-03-27 14:41:00 | Complement Factor I Gene Polymorphism in a Turkish Age-Related Macular Degeneration Population. | 31614353 |
| 2020-01-18 11:02:00 | we identified the prognostic value of two proteases, ADAM-10 and complement factor I, for high-grade serous ovarian cancer which could have clinical significance. | 30987833 |
| 2019-11-02 10:32:00 | performed sequence analysis of the complement genes complement factor H (CFH), complement factor I (CFI), and complement C3 (C3) in 866 aHUS/C3G and 697 AMD patients. In total, we identified 505 low-frequency alleles, representing 121 unique variants, of which 51 are novel | 29888403 |
| 2019-09-28 12:51:00 | Oxidized CFH enhances Factor I mediated cleavage of C3 and C3b whereas the reduced form loses this activity in age-related macular degeneration. | 30253188 |
| Type | IDs |
|---|---|
| Synonymous | AHUS3, ARMD13, C3BINA, C3b-INA, FI, IF, KAF |
| Gene |
UniProtKB-ID:
CFAI_HUMAN,
B4DRF2_HUMAN,
Q8WW88_HUMAN,
A8K3L0_HUMAN,
G3XAM2_HUMAN
UniprotKB:
P05156,
B4DRF2,
Q8WW88,
A8K3L0,
G3XAM2
UniParc:
UPI000006EFC6,
UPI00015DA6A7,
UPI0000D615A9,
UPI00017A7BD9,
UPI000013D5C9
EMBL:
AC126283,
Y00318,
AF005095,
AK290625,
CH471057,
AK299232,
BC020718,
J02770
Ensembl:
ENSG00000205403
KO:
hsa:3426
|
| Nucleutide sequences |
EMBL-CDS:
AAA52455.1,
CAA68416.1,
AAC08733.2,
BAG61264.1,
AAH20718.1,
BAF83314.1,
EAX06251.1
Gene_ORFName:
hCG_21044
Ensembl_TRS:
ENST00000394634,
ENST00000512148
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000378130,
ENSP00000427438
RefSeq:
NP_001317964.1,
NP_001362210.1,
NP_001362209.1,
NP_001362211.1,
NP_000195.3,
XP_011530222.1,
XP_006714273.1,
NP_001362213.1,
NP_001362207.1,
NP_001362212.1,
NP_001304986.2,
XP_016863655.1,
NP_001362208.1
|
| Others |
UniRef100:
UniRef100_A8K3L0,
UniRef100_B4DRF2,
UniRef100_P05156,
UniRef100_Q8WW88,
UniRef100_G3XAM2
UniRef90:
UniRef90_A0A087X0I2,
UniRef90_P05156
UniRef50:
UniRef50_A0A670ISD4,
UniRef50_P05156
UniGene:
Hs.312485
CCDS:
CCDS34049.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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