| Type | Description |
|---|---|
| Definition | beta-site APP-cleaving enzyme |
| Date | Results | Publications |
|---|---|---|
| 2011-10-01 11:25:00 | Data suggest that inhibition of gamma-secretase and disruption of the Notch developmental pathway potentially contribute to mercury-induced toxicity in the nervous system. | 21415381 |
| 2010-01-21 00:00:00 | identified two candidate Drosophila aspartic proteases that are homologous to human BACE1, DASP1 and DASP2, and demonstrated that when these proteases were cotransfected with Drosophila HS6ST, they induced the secretion of the transferase [DASP2] | 15809332 |
| Type | IDs |
|---|---|
| Synonymous | CG13095, DASP2, Dmel\CG13095, anon-WO0140519.142, dBACE, dBace |
| Gene |
UniProtKB-ID:
Q9VLK3_DROME
UniprotKB:
Q9VLK3
UniParc:
UPI0000075F92
EMBL:
BT016133,
AE014134
EnsemblGenome:
FBgn0032049
KO:
dme:Dmel_CG13095
|
| Nucleutide sequences |
EMBL-CDS:
AAF52686.1,
AAV37018.1,
AHN54270.1
Gene_ORFName:
CG13095,
Dmel_CG13095
EnsemblGenome_TRS:
FBtr0343427,
FBtr0079701
|
| Protein sequencees |
EnsemblGenome_PRO:
FBpp0310072,
FBpp0079309
RefSeq:
NP_001285756.1,
NP_609235.1
|
| Others |
UniRef100:
UniRef100_Q9VLK3
UniRef90:
UniRef90_Q9VLK3
UniRef50:
UniRef50_Q9VLK3
UniGene:
Dm.33539
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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