Type | Description |
---|---|
Definition | NIMA related kinase 5 |
Date | Results | Publications |
---|---|---|
2021-03-20 13:25:00 | Knockdown of lncRNA XIST inhibits hypoxia-induced glycolysis, migration and invasion through regulating miR-381-3p/NEK5 axis in nasopharyngeal carcinoma. | 32196601 |
2020-09-19 16:23:00 | NEK5 interacts with topoisomerase IIbeta and is involved in the DNA damage response induced by etoposide. | 31090963 |
2020-06-20 10:25:00 | the NEK protein kinases emerge as important proteins in thyroid cancer development and may help to identify malignancy and aggressiveness features during diagnosis. | 31906878 |
2019-11-09 12:47:00 | Data show that up-regulated NEK5 was significantly associated with breast tumor progression and poor overall prognosis; and that silencing of NEK5 can significantly suppress the proliferation both in vivo and in vitro, inhibiting migration, and invasion. NEK5 can up-regulate Cyclin A2 by direct interaction. | 30675923 |
2015-12-26 12:13:00 | The hNek5 is mitochondrial localization and its role on cell death and cell respiration defects through COX11, MTX2 and BCLAF1. | 25725288 |
Type | IDs |
---|---|
Gene |
UniProtKB-ID:
NEK5_HUMAN
UniprotKB:
Q6P3R8
UniParc:
UPI0000227E77
EMBL:
AL139082,
BC063885
Ensembl:
ENSG00000197168
KO:
hsa:341676
|
Nucleutide sequences |
EMBL-CDS:
AAH63885.1
Ensembl_TRS:
ENST00000355568,
ENST00000617045
|
Protein sequencees |
Ensembl_PRO:
ENSP00000477810,
ENSP00000347767
RefSeq:
XP_016876046.1,
XP_016876045.1,
XP_006719871.2,
NP_954983.1,
XP_011533368.1,
NP_001352481.1,
XP_016876044.1,
XP_011533370.1
|
Others |
UniRef100:
UniRef100_Q6P3R8
UniRef90:
UniRef90_Q6P3R8
UniRef50:
UniRef50_Q6P3R8
UniGene:
Hs.672144
CCDS:
CCDS31979.1
|
{{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
---|---|---|---|---|---|---|---|---|
Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
暂无数据
Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
---|---|---|---|
32196601 |
Eur Rev Med Pharmacol Sci C-H Zhao , X-F Bai , X-H Hu |
2020-03-01 | - |
31906878 |
Expression of the NEK family in normal and cancer tissue: an immunohistochemical study. BMC Cancer Talita Diniz Melo-Hanchuk , Mariana Bonjiorno Martins , Lucas Leite Cunha , Fernando Augusto Soares , Laura Sterian Ward , José Vassallo , Jörg Kobarg |
2020-01-06 | - |
31090963 |
J Cell Biochem Talita Diniz Melo-Hanchuk , Priscila Ferreira Slepicka , Alessandra Luiza Pelegrini , Carlos Frederico Martins Menck , Jörg Kobarg |
2019-10-01 | - |
30675923 |
NEK5 promotes breast cancer cell proliferation through up-regulation of Cyclin A2. Mol Carcinog Jing Pei , Jing Zhang , Xiaowei Yang , Zhengsheng Wu , Chenyu Sun , Zhaorui Wang , Benzhong Wang |
2019-06-01 | - |
29987050 |
Proc. Natl. Acad. Sci. U.S.A. Tengfei Xiao , Wei Li , Xiaoqing Wang , Han Xu , Jixin Yang , Qiu Wu , Ying Huang , Joseph Geradts , Peng Jiang , Teng Fei , David Chi , Chongzhi Zang , Qi Liao , Jonathan Rennhack , Eran Andrechek , Nanlin Li , Simone Detre , Mitchell Dowsett , Rinath M Jeselsohn , X Shirley Liu , Myles Brown |
2018-07-31 | - |
27173435 |
An organelle-specific protein landscape identifies novel diseases and molecular mechanisms. Nat Commun Karsten Boldt , Jeroen van Reeuwijk , Qianhao Lu , Konstantinos Koutroumpas , Thanh-Minh T Nguyen , Yves Texier , Sylvia E C van Beersum , Nicola Horn , Jason R Willer , Dorus A Mans , Gerard Dougherty , Ideke J C Lamers , Karlien L M Coene , Heleen H Arts , Matthew J Betts , Tina Beyer , Emine Bolat , Christian Johannes Gloeckner , Khatera Haidari , Lisette Hetterschijt , Daniela Iaconis , Dagan Jenkins , Franziska Klose , Barbara Knapp , Brooke Latour , Stef J F Letteboer , Carlo L Marcelis , Dragana Mitic , Manuela Morleo , Machteld M Oud , Moniek Riemersma , Susan Rix , Paulien A Terhal , Grischa Toedt , Teunis J P van Dam , Erik de Vrieze , Yasmin Wissinger , Ka Man Wu , Gordana Apic , Philip L Beales , Oliver E Blacque , Toby J Gibson , Martijn A Huynen , Nicholas Katsanis , Hannie Kremer , Heymut Omran , Erwin van Wijk , Uwe Wolfrum , François Kepes , Erica E Davis , Brunella Franco , Rachel H Giles , Marius Ueffing , Robert B Russell , Ronald Roepman , UK10K Rare Diseases Group |
2016-05-13 | - |
25725288 |
Cell. Signal. Talita D Melo Hanchuk , Priscila Ferreira Papa , Paolo G La Guardia , Anibal E Vercesi , Jörg Kobarg |
2015-06-01 |
NEK5
|
25963817 |
Nek5 promotes centrosome integrity in interphase and loss of centrosome cohesion in mitosis. J. Cell Biol. Suzanna L Prosser , Navdeep K Sahota , Laurence Pelletier , Ciaran G Morrison , Andrew M Fry |
2015-05-11 | - |
15489334 |
Genome Res. Daniela S Gerhard , Lukas Wagner , Elise A Feingold , Carolyn M Shenmen , Lynette H Grouse , Greg Schuler , Steven L Klein , Susan Old , Rebekah Rasooly , Peter Good , Mark Guyer , Allison M Peck , Jeffery G Derge , David Lipman , Francis S Collins , Wonhee Jang , Steven Sherry , Mike Feolo , Leonie Misquitta , Eduardo Lee , Kirill Rotmistrovsky , Susan F Greenhut , Carl F Schaefer , Kenneth Buetow , Tom I Bonner , David Haussler , Jim Kent , Mark Kiekhaus , Terry Furey , Michael Brent , Christa Prange , Kirsten Schreiber , Nicole Shapiro , Narayan K Bhat , Ralph F Hopkins , Florence Hsie , Tom Driscoll , M Bento Soares , Tom L Casavant , Todd E Scheetz , Michael J Brown-stein , Ted B Usdin , Shiraki Toshiyuki , Piero Carninci , Yulan Piao , Dawood B Dudekula , Minoru S H Ko , Koichi Kawakami , Yutaka Suzuki , Sumio Sugano , C E Gruber , M R Smith , Blake Simmons , Troy Moore , Richard Waterman , Stephen L Johnson , Yijun Ruan , Chia Lin Wei , S Mathavan , Preethi H Gunaratne , Jiaqian Wu , Angela M Garcia , Stephen W Hulyk , Edwin Fuh , Ye Yuan , Anna Sneed , Carla Kowis , Anne Hodgson , Donna M Muzny , John McPherson , Richard A Gibbs , Jessica Fahey , Erin Helton , Mark Ketteman , Anuradha Madan , Stephanie Rodrigues , Amy Sanchez , Michelle Whiting , Anup Madari , Alice C Young , Keith D Wetherby , Steven J Granite , Peggy N Kwong , Charles P Brinkley , Russell L Pearson , Gerard G Bouffard , Robert W Blakesly , Eric D Green , Mark C Dickson , Alex C Rodriguez , Jane Grimwood , Jeremy Schmutz , Richard M Myers , Yaron S N Butterfield , Malachi Griffith , Obi L Griffith , Martin I Krzywinski , Nancy Liao , Ryan Morin , Ryan Morrin , Diana Palmquist , Anca S Petrescu , Ursula Skalska , Duane E Smailus , Jeff M Stott , Angelique Schnerch , Jacqueline E Schein , Steven J M Jones , Robert A Holt , Agnes Baross , Marco A Marra , Sandra Clifton , Kathryn A Makowski , Stephanie Bosak , Joel Malek , MGC Project Team |
2004-10-01 |
Ldlrap1,
Dnajc3,
Rnaset2a,
Btnl1,
Isg15,
Cyp3a41b,
Ly6c2,
Ccl21b,
Eif3j2,
Mup18,
Lrrc19,
Rcc1,
1700047I17Rik2,
Pcsk9,
Adat3,
Tdrd7,
Sco2,
Gpr153,
Pafah2,
Gm44504,
H6pd,
Adprhl2,
Gpn2,
Rusc2,
Stx12,
Ppp1r8,
Smpdl3b,
Fam46b,
Bsdc1,
Slc44a1,
Zfand2a,
Rubcn,
Kifc1,
Pifo,
C030017K20Rik,
Cbarp,
Rpl5,
Micalcl,
Atg14,
Lrrc8c,
Noc4l,
Nsun5,
Psph,
Trrap,
Mapre3,
Ube3c,
Tbc1d14,
Hscb,
Tyw1,
Emilin1,
Rab28,
Pot1a,
Parp11,
Tada3,
Tra2a,
Brk1,
Fbxl14,
Phrf1,
Plekha1,
Gm21975,
Ric8a,
Mob2,
Prkd2,
Ccp110,
Vrk3,
Grwd1,
Nlrp6,
Trim68,
Psip1,
Spred3,
Faap24,
Ints4,
Rrp8,
Unc45a,
Igflr1,
Sf3b3,
D8Ertd738e,
Usb1,
Champ1,
Smim19,
Exoc8,
Gadd45gip1,
Phkb,
Dohh,
Fam192a,
Enkd1,
Taf5l,
Zdhhc7,
Snapc2,
Ak6,
Gpat4,
Dcun1d2,
Ankrd10,
Cog4,
Hinfp,
Lars2,
Xylb,
Imp3,
Cmtm7
|
15057823 |
The DNA sequence and analysis of human chromosome 13. Nature A Dunham , L H Matthews , J Burton , J L Ashurst , K L Howe , K J Ashcroft , D M Beare , D C Burford , S E Hunt , S Griffiths-Jones , M C Jones , S J Keenan , K Oliver , C E Scott , R Ainscough , J P Almeida , K D Ambrose , D T Andrews , R I S Ashwell , A K Babbage , C L Bagguley , J Bailey , R Bannerjee , K F Barlow , K Bates , H Beasley , C P Bird , S Bray-Allen , A J Brown , J Y Brown , W Burrill , C Carder , N P Carter , J C Chapman , M E Clamp , S Y Clark , G Clarke , C M Clee , S C M Clegg , V Cobley , J E Collins , N Corby , G J Coville , P Deloukas , P Dhami , I Dunham , M Dunn , M E Earthrowl , A G Ellington , L Faulkner , A G Frankish , J Frankland , L French , P Garner , J Garnett , J G R Gilbert , C J Gilson , J Ghori , D V Grafham , S M Gribble , C Griffiths , R E Hall , S Hammond , J L Harley , E A Hart , P D Heath , P J Howden , E J Huckle , P J Hunt , A R Hunt , C Johnson , D Johnson , M Kay , A M Kimberley , A King , G K Laird , C J Langford , S Lawlor , D A Leongamornlert , D M Lloyd , C Lloyd , J E Loveland , J Lovell , S Martin , M Mashreghi-Mohammadi , S J McLaren , A McMurray , S Milne , M J F Moore , T Nickerson , S A Palmer , A V Pearce , A I Peck , S Pelan , B Phillimore , K M Porter , C M Rice , S Searle , H K Sehra , R Shownkeen , C D Skuce , M Smith , C A Steward , N Sycamore , J Tester , D W Thomas , A Tracey , A Tromans , B Tubby , M Wall , J M Wallis , A P West , S L Whitehead , D L Willey , L Wilming , P W Wray , M W Wright , L Young , A Coulson , R Durbin , T Hubbard , J E Sulston , S Beck , D R Bentley , J Rogers , M T Ross |
2004-04-01 |
LOC100129307,
CCT5-2P,
GPC6,
FRY,
MBNL2,
FARP1,
LPAR6,
LHFP,
LOC101928697,
TRIM13,
MRPS31,
SPRY2,
SAP18,
TUBGCP3,
PIBF1,
POSTN,
HSPH1,
WASF3,
RCBTB2,
WBP4,
AKAP11,
KLF12,
ADPRHL1,
SLITRK1,
ARL11,
TEX29,
TEX26,
PRR20A,
SPACA7,
COL4A1,
COL4A2,
CPB2,
RNF113B,
PARP4,
B3GLCT,
DACH1,
DGKH,
GPR180,
STOML3,
DCT,
COMMD6,
EFNB2,
ESD,
F7,
AMER2,
USP12,
GSX1,
SKA3,
MICU2,
SPATA13,
LNX2,
FGF9,
FGF14,
GPC5,
FNDC3A,
DIS3,
MYCBP2,
FOXO1,
ZC3H13,
SPG20,
ATP11A,
DOCK9,
TGDS,
ALOX5AP,
ZDHHC20,
PAN3,
SLITRK5,
SACS,
INTS6,
CKAP2,
HS6ST3,
DAOA,
NUFIP1,
GJA3,
GJB2,
OXGR1,
PCDH17,
CHAMP1,
GPR12,
GPR18,
MLNR,
RGCC,
MED4,
DNAJC15,
HTR2A,
UBAC2,
FREM2,
NEK5,
TMEM255B,
SERP2,
LIG4,
ATP4B,
PCDH9,
VPS36,
POLR1D,
CRYL1,
PHF11,
POMP,
UFM1
|
排名 | 科研单位 | 文献 |
---|---|---|
{{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
排名 | 研究人员 | 文献 |
---|---|---|
{{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员