| Type | Description |
|---|---|
| Definition | chromosome X open reading frame 67 |
| Date | Results | Publications |
|---|---|---|
| 2020-08-12 10:48:00 | High EZHIP expression is associated with posterior fossa ependymoma. | 30923826 |
| 2020-06-27 10:07:00 | CATACOMB as the potential interlocutor between DNA methylation and PRC2 activity. | 31281901 |
| 2019-12-21 12:05:00 | Study reports the identification of a cofactor of PRC2, EZHIP (EZH1/2 Inhibitory Protein), expressed predominantly in the gonads. EZHIP limits the enzymatic activity of PRC2 and lessens the interaction between the core complex and its accessory subunits but does not interfere with PRC2 recruitment to chromatin. Study uncovers EZHIP as a regulator of chromatin landscape in gametes. | 31451685 |
| 2019-10-12 13:00:00 | The data of this study suggested that heterogeneity among PFA ependymomas could have clinicopathologic utility and that CXorf67 may have a functional role in these tumors. | 29909548 |
| 2019-06-15 12:28:00 | Study revealed that CXORF67 contains a highly conserved "K27M-like" sequence that is necessary and sufficient to inhibit PRC2 activity and reduce cellular H3K27me3 levels. Biochemical and cell-based studies demonstrate that CXORF67 functions as a K27M-like peptidyl inhibitor of PRC2. Therefore, study propose the name EZHIP (Enhancer of Zeste Homologs Inhibitory Protein) as a more descriptive for the function of CXORF67. | 31086175 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
EZHIP_HUMAN,
A0A515VFR0_HUMAN
UniprotKB:
Q86X51,
A0A515VFR0
UniParc:
UPI000000DB6D
EMBL:
MK321327,
BC046248,
CH471180
Ensembl:
ENSG00000187690
KO:
hsa:340602
|
| Nucleutide sequences |
EMBL-CDS:
AAH46248.1,
EAW89908.1,
QDN53946.1
Ensembl_TRS:
ENST00000342995
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000342680
RefSeq:
NP_981952.1
|
| Others |
UniRef100:
UniRef100_Q86X51
UniRef90:
UniRef90_Q86X51
UniRef50:
UniRef50_Q86X51
UniGene:
Hs.97053
CCDS:
CCDS78485.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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