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340273 ABCB5

340273

ABCB5

ATP binding cassette subfamily B member 5

protein-coding

Homo sapiens

基因描述

Type Description
Definition ATP binding cassette subfamily B member 5

研究结论

Date Results Publications
2021-04-13 10:14:00 IS THERE A CLINICAL PATHOLOGICAL CORRELATION OF COLORECTAL ADENOCARCINOMA WITH THE IMMUNOHISTOCHEMICAL EXPRESSION OF OPN AND ABCB5? 33759959
2020-12-26 13:11:00 Targeting the ABC transporter ABCB5 sensitizes glioblastoma to temozolomide-induced apoptosis through a cell-cycle checkpoint regulation mechanism. 32317280
2020-11-21 13:30:00 ABCB5 is activated by MITF and beta-catenin and is associated with melanoma differentiation. 31595650
2020-06-20 12:58:00 ABCB5 was mutated in 13.75% of the 640 melanoma samples analyzed. Studies in four melanoma cell lines with various genetic backgrounds showed an increase in the proliferation and migration capacity of mutant ABCB5-expressing cells, suggesting that ABCB5 plays a role in the development of melanoma as a tumor suppressor gene. 30905807
2020-02-15 12:32:00 ABCB5 may represent a new target to chemosensitize MPM IC and a potential biomarker to predict the response to the first-line chemotherapy in malignant pleural mesothelioma patients 31107974

名称对应

Type IDs
Synonymous ABCB5alpha, ABCB5beta, EST422562
Gene
UniProtKB-ID: ABCB5_HUMAN, A0A024RA03_HUMAN
UniprotKB: Q2M3G0, A0A024RA03
UniParc: UPI000153D987, UPI000173A253, UPI0000046C22, UPI0000367440
EMBL: CH471073, BC110370, AY234788, GU437216, AC002486, AF399931, BC104894, AY851365, AY230001, GU437217, AB353947, AY090613, AY851364, BC104920, CH236948, AF319622, AC005060
Ensembl: ENSG00000004846
KO: hsa:340273
Nucleutide sequences
EMBL-CDS: BAF75364.1, AAN76500.1, AAI04921.1, AAM09027.1, EAL24273.1, AAW31629.1, AAP55848.1, AAO73470.1, AAQ03033.1, AAI04895.2, ADV32637.1, ADV32636.1, EAW93726.1, AAW31630.1, EAW93727.1
Gene_ORFName: hCG_38926
Ensembl_TRS: ENST00000404938, ENST00000406935, ENST00000258738, ENST00000443026
Protein sequencees
Ensembl_PRO: ENSP00000258738, ENSP00000406730, ENSP00000383899, ENSP00000384881
RefSeq: NP_001157413.1, NP_001157414.1, NP_848654.3, XP_011513669.1, NP_001157465.1
Others
UniRef100: UniRef100_A0A024RA03, UniRef100_Q2M3G0
UniRef90: UniRef90_Q2M3G0, UniRef90_A0A2I3H1B4
UniRef50: UniRef50_Q2M3G0, UniRef50_A0A2I3H1B4
UniGene: Hs.404102
CCDS: CCDS55090.1, CCDS55092.1, CCDS55091.1, CCDS5371.1

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