| Type | Description |
|---|---|
| Definition | inhibitor of DNA binding 4, HLH protein |
| Date | Results | Publications |
|---|---|---|
| 2021-02-27 13:47:00 | Paracrine Signaling from Breast Causes Activation of ID4 Expression in Tumor-Associated Macrophages. | 32054109 |
| 2020-11-21 13:25:00 | Proteogenomic analysis of Inhibitor of Differentiation 4 (ID4) in basal-like breast cancer. | 32527287 |
| 2020-06-20 11:19:00 | miR-335/ID4 dysregulation facilitated leukemogenesis through the activation of the PI3K/Akt signaling pathway. | 31147526 |
| 2019-07-20 12:41:00 | Data propose that ID4 is frequently silenced by promoter methylation in ER+ breast cancers and functions as a tumor suppressor gene in these tumors, probably due to its interaction with key genes of the ER pathway. | 30139383 |
| 2019-05-11 12:19:00 | At the molecular level, ID4 protein expression in breast cancer cells controls, through paracrine signalling, the activation of an angiogenic programme in macrophages. This programme includes both the increase of angiogenesis-related mRNAs and the decrease of members of the anti-angiogenic miR-15b/107 group. | 29921315 |
| Type | IDs |
|---|---|
| Synonymous | IDB4, bHLHb27 |
| Gene |
UniProtKB-ID:
ID4_HUMAN
UniprotKB:
P47928
UniParc:
UPI000012D193
EMBL:
U28368,
AL022726,
Y07958,
U16153,
BC014941
Ensembl:
ENSG00000172201
KO:
hsa:3400
|
| Nucleutide sequences |
EMBL-CDS:
AAA73923.1,
AAH14941.1,
AAA82882.1,
CAA69255.1
Ensembl_TRS:
ENST00000378700
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000367972
RefSeq:
NP_001537.1
|
| Others |
UniRef100:
UniRef100_P47928
UniRef90:
UniRef90_P47928
UniRef50:
UniRef50_P41139
UniGene:
Hs.519601,
Hs.663469
CCDS:
CCDS4544.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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