| Type | Description |
|---|---|
| Definition | inhibitor of DNA binding 2 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-17 13:12:00 | MITF is a driver oncogene and potential therapeutic target in kidney angiomyolipoma tumors through transcriptional regulation of CYR61. | 33082558 |
| 2020-08-12 15:05:00 | The study observed higher expression levels of HDGFRP3 and ID2 in bipolar disorder (BD) patients who favourably respond to lithium. Both of these genes are involved in neurogenesis. | 28854847 |
| 2020-07-18 10:50:00 | Long noncoding RNA ANCR inhibits the differentiation of mesenchymal stem cells toward definitive endoderm by facilitating the association of PTBP1 with ID2. | 31235689 |
| 2020-06-20 10:14:00 | ID2-AS1 significantly suppressed the migration, invasion and metastasis of hepatocellular carcinoma (HCC) cells in vitro and in vivo. Mechanistically, ID2-AS1 regulated the transcription of its adjacent gene inhibitor of DNA binding 2 (ID2) by blocking the binding of histone deacetylase 8 (HDAC8) on the ID2 enhancer | 31730902 |
| 2019-08-24 11:18:00 | We have identified ID2 as a key factor of DCIS initiation and GJB2 and INHBA as aggressive factors during progression of ID2-mediated DCIS to IDC. ID2 is capable of promoting the cancer stem cell population in pre-malignant cells and leads to DCIS formation | 30725231 |
| Type | IDs |
|---|---|
| Synonymous | GIG8, ID2A, ID2H, bHLHb26 |
| Gene |
UniProtKB-ID:
ID2_HUMAN,
Q53T66_HUMAN
UniprotKB:
Q02363,
Q53T66
UniParc:
UPI00000012EE
EMBL:
M97796,
AY634687,
D13891,
CH471053,
AC011747,
AK311988,
BC030639
Ensembl:
ENSG00000115738
KO:
hsa:3398
|
| Nucleutide sequences |
EMBL-CDS:
AAH30639.1,
BAA02990.1,
AAA58681.1,
EAX01019.1,
BAG34927.1,
AAY14810.1,
EAX01018.1,
AAV35470.1
Gene_ORFName:
hCG_1784377
Ensembl_TRS:
ENST00000396290,
ENST00000331129,
ENST00000234091
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000385465,
ENSP00000379585,
ENSP00000234091
RefSeq:
NP_002157.2
|
| Others |
UniRef100:
UniRef100_Q02363
UniRef90:
UniRef90_Q02363
UniRef50:
UniRef50_Q02363
UniGene:
Hs.180919,
Hs.726053
CCDS:
CCDS1659.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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