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3396 MRPL58

3396

MRPL58

mitochondrial ribosomal protein L58

protein-coding

Homo sapiens

基因描述

Type Description
Definition mitochondrial ribosomal protein L58

研究结论

Date Results Publications
2019-02-23 11:07:00 miR-1301-3p inhibits cell proliferation via inducing cell cycle arrest and apoptosis through targeting ICT1, and might be a therapeutic target for BC. 29951881
2018-09-01 11:27:00 High ICT1 expression is associated with leukemia. 29328466
2018-07-28 11:26:00 ICT1 overexpression notably predicted poor prognosis of gastric cancer patients. 28987942
2018-07-28 11:25:00 Study demonstrates that ICT1 overexpression correlates with malignant clinical features and poor prognosis of hepatocellular carcinoma (HCC) patients. Functionally, ICT1 promotes proliferation, cell cycle progression and inhibits apoptosis of HCC cells. ICT1 regulates the expressions of CDK1, cyclin B1, Bcl-2 and Bax, and is directly targeted by microRNA-134 (miR-134) in HCC cells. 29130100
2018-05-19 11:54:00 ICT1 may play a crucial role in promoting gastric cancer proliferation in vitro. 29036264

名称对应

Type IDs
Synonymous DS-1, DS1, ICT1, MRP-L58
Gene
UniProtKB-ID: ICT1_HUMAN
UniprotKB: Q14197
UniParc: UPI0000000DF2
EMBL: X81788, AK222553, BC015335, BT007111, CH471099, AK314138
Ensembl: ENSG00000167862
KO: hsa:3396
Nucleutide sequences
EMBL-CDS: BAG36828.1, CAA57387.1, AAH15335.1, EAW89227.1, AAP35775.1, BAD96273.1
Ensembl_TRS: ENST00000301585
Protein sequencees
Ensembl_PRO: ENSP00000301585
RefSeq: NP_001290194.1, XP_016880063.1, NP_001536.1
Others
UniRef100: UniRef100_Q14197
UniRef90: UniRef90_Q14197
UniRef50: UniRef50_Q14197
UniGene: Hs.407955
CCDS: CCDS11711.1

全选

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研究热度

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