| Type | Description |
|---|---|
| Definition | transcription factor AP-2 epsilon |
| Date | Results | Publications |
|---|---|---|
| 2019-11-30 11:09:00 | In the present study, it was demonstrated that hypermethylation of TFAP2E resulted in its reduced expression and 5FU chemoresistance in gastric cancer (GC) cells. miRNAs miR106a5p and miR421 were highly expressed and regulated the chemoresistance induced by TFAP2E methylation. | 31115533 |
| 2019-11-23 10:32:00 | TFAP2E methylation and expression may not play a major role in predicting response to 5-FU-based chemotherapy in patients with colorectal cancer. | 29535127 |
| 2017-04-22 12:18:00 | Results showed that lower expression levels of TFAP2E are significantly associated with a shorter survival of patients with neuroblastoma indicating that TFAP2E acts as a tumor suppressor of neuroblastoma. | 28260105 |
| 2016-12-17 11:31:00 | Hypermethylation of TFAP2E was associated with lack of response to fluorouracil-based chemotherapy, indicating that it might be a potential predictor of treatment response in patients with gastric cancer. | 25810491 |
| 2015-02-28 13:09:00 | AP-2E was frequently hypermethylated in tumors from patients with colorectal cancer | 24996990 |
| Type | IDs |
|---|---|
| Synonymous | AP2E |
| Gene |
UniProtKB-ID:
AP2E_HUMAN
UniprotKB:
Q6VUC0
UniParc:
UPI0000203EFC
EMBL:
AL157951,
BC041175,
AY326454,
CH471059,
AC004865
Ensembl:
ENSG00000116819
KO:
hsa:339488
|
| Nucleutide sequences |
EMBL-CDS:
AAQ91614.1,
EAX07409.1,
CAI23520.1,
AAH41175.1
Ensembl_TRS:
ENST00000373235
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000362332
RefSeq:
XP_016856628.1,
NP_848643.2
|
| Others |
UniRef100:
UniRef100_Q6VUC0
UniRef90:
UniRef90_Q6VUC0
UniRef50:
UniRef50_P34056-4
UniGene:
Hs.567844
CCDS:
CCDS393.2
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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