| Type | Description |
|---|---|
| Definition | MSL complex subunit 1 |
| Date | Results | Publications |
|---|---|---|
| 2015-10-31 10:36:00 | Studies identi fi ed a novel signal of nuclear localization (NLS) in all MSL1 protein isoforms and found that the combination of both NLS allows for its intra-nuclear focal accumulation and nuclear transport of TTC4 while all MSL1 isoforms affect H4K16Ac. | 24913909 |
| 2014-09-20 11:09:00 | The MSL1 bound to Nupr1, with a moderate affinity (2.8 microM) in an entropically-driven process. MSL1 did not bind to non-damaged DNA, but it bound to chemically-damaged-DNA with a moderate affinity (1.2 microM) also in an entropically-driven process. | 24205110 |
| 2010-01-21 00:00:00 | MSL1 plays an important role in mediating irradiation-induced DNA repair through formation of HAT complexes and interaction with 53BP1. P8 acts as a negative regulator of this process by interacting with MSL1 and preventing its role on HAT activity. | 19650074 |
| 2006-11-20 16:51:00 | A multisubunit human histone acetylase complex that contains homologs of the Drosophila MSL proteins MOF, MSL1 (hampin A), MSL2, and MSL3 was described. This complex is responsible for histone H4 lysine-16 acetylation of all cellular chromosomes. | 16227571 |
| Type | IDs |
|---|---|
| Synonymous | MSL-1 |
| Gene |
UniProtKB-ID:
MSL1_HUMAN,
B3KWR7_HUMAN
UniprotKB:
Q68DK7,
B3KWR7
UniParc:
UPI0000DBE498,
UPI0000200C58,
UPI00001D79E6,
UPI0000200C56
EMBL:
CR749360,
BC122543,
BC118997,
AL049450,
AK125654,
AC068669
Ensembl:
ENSG00000188895
KO:
hsa:339287
|
| Nucleutide sequences |
EMBL-CDS:
AAI22544.1,
CAH10734.1,
AAI18998.1,
CAH18213.1,
BAG54229.1
Ensembl_TRS:
ENST00000579565,
ENST00000398532
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000462945,
ENSP00000381543
RefSeq:
NP_001352849.1,
NP_001352848.1,
NP_001352850.1,
NP_001012241.1
|
| Others |
UniRef100:
UniRef100_B4DMT3,
UniRef100_Q68DK7
UniRef90:
UniRef90_Q6PDM1
UniRef50:
UniRef50_Q6PDM1
UniGene:
Hs.532786
CCDS:
CCDS45670.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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