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339221 ENPP7

339221

ENPP7

ectonucleotide pyrophosphatase/phosphodiesterase 7

protein-coding

Homo sapiens

基因描述

Type Description
Definition ectonucleotide pyrophosphatase/phosphodiesterase 7

研究结论

Date Results Publications
2017-07-15 11:54:00 human alkaline sphingomyelinase crystal structure provides insights into substrate recognition 28292932
2015-04-18 12:11:00 NPP7 activity and the ratio of 1.4/1.2 kb products in bile are significantly decreased in malignancy, particularly in cholangiocarcinoma. 25100243
2012-06-23 10:39:00 The F275A mutation of NPP7 showed impaired catalytic function whereas L107F mutation showed enhanced catalytic activity. 22177013
2010-11-06 11:06:00 predict the three-dimensional structure of NPP7 by homology modeling using a recently crystallized NPP from bacteria. Using the model, we studied the substrate specificity of the enzyme by docking. 20839774
2010-01-21 00:00:00 alk-SMase activity is severely affected by defective N-glycosylation at 5 sites and by structural alterations of the putative metal-binding sites and the predicted active core. 15458386

名称对应

Type IDs
Synonymous ALK-SMase, E-NPP 7, NPP-7, NPP7
Gene
UniProtKB-ID: ENPP7_HUMAN
UniprotKB: Q6UWV6
UniParc: UPI00001983C8
EMBL: AY230663, AY358622, AK126250, BC041453
Ensembl: ENSG00000182156
KO: hsa:339221
Nucleutide sequences
EMBL-CDS: BAC86504.1, AAH41453.2, AAP69661.1, AAQ88985.1
Gene_ORFName: UNQ3077/PRO9912
Ensembl_TRS: ENST00000328313
Protein sequencees
Ensembl_PRO: ENSP00000332656
RefSeq: XP_011523039.1, NP_848638.3
Others
UniRef100: UniRef100_Q6UWV6
UniRef90: UniRef90_Q6UWV6
UniRef50: UniRef50_Q6UWV6
UniGene: Hs.114084
CCDS: CCDS11763.1

全选

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研究热度

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