| Type | Description |
|---|---|
| Definition | apolipoprotein B mRNA editing enzyme catalytic subunit 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-01-23 13:04:00 | APOBEC1 cytosine deaminase activity on single-stranded DNA is suppressed by replication protein A. | 33330905 |
| 2018-11-03 11:51:00 | Our findings propose APOBEC1 and isoform b as the potential endogenous mutators implicated in cancer in-frame indels and pave the way for their use as novel prognostic tumor markers. | 29346513 |
| 2017-07-15 10:49:00 | Luciferase-fused 3' untranslated region of human Dickkopf1 activity was highly upregulated in A1CF-overexpressed MCF7 cells, but this upregulation can be inhibited by mutating conserved binding motifs of Dickkopf1 3' untranslated region. A1CF played a crucial role in cell migration and survival through affecting 3' untranslated region of Dickkopf1 to upregulate its expression in MCF7 cells. | 28639893 |
| 2016-08-13 11:53:00 | AICDA/APOBEC family of cytidine deaminases is significant in innate immunity, as it restricts numerous viruses, including HBV, through hypermutationdependent and independent mechanisms. (Review) | 26398702 |
| 2015-06-20 11:27:00 | Results show that expression of APOBEC1 induces a mutator phenotype in 2 different cellular models. | 25085003 |
| Type | IDs |
|---|---|
| Synonymous | APOBEC-1, BEDP, CDAR1, HEPR |
| Gene |
UniProtKB-ID:
ABEC1_HUMAN
UniprotKB:
P41238
UniParc:
UPI000013C8F4
EMBL:
U72891,
L25877,
AB009426,
L26234,
U78720
Ensembl:
ENSG00000111701
KO:
hsa:339
|
| Nucleutide sequences |
EMBL-CDS:
BAA23882.1,
AAD10701.1,
AAA64230.1,
AAA86766.1,
AAD00185.1
Ensembl_TRS:
ENST00000229304
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000229304
RefSeq:
NP_005880.2,
NP_001635.2,
NP_001291495.1
|
| Others |
UniRef100:
UniRef100_P41238
UniRef90:
UniRef90_P41238
UniRef50:
UniRef50_P41238
UniGene:
Hs.560
CCDS:
CCDS8579.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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