A reference map of the human binary protein interactome.

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CCDC84 Acetylation Oscillation Regulates Centrosome Duplication by Modulating HsSAS-6 Degradation.

Cell Rep     Tianning Wang , Yuhong Zou , Ning Huang , Junlin Teng , Jianguo Chen

Mapping the Genetic Landscape of Human Cells.

Cell     Max A Horlbeck , Albert Xu , Min Wang , Neal K Bennett , Chong Y Park , Derek Bogdanoff , Britt Adamson , Eric D Chow , Martin Kampmann , Tim R Peterson , Ken Nakamura , Michael A Fischbach , Jonathan S Weissman , Luke A Gilbert

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

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Architecture of the human interactome defines protein communities and disease networks.

Nature     Edward L Huttlin , Raphael J Bruckner , Joao A Paulo , Joe R Cannon , Lily Ting , Kurt Baltier , Greg Colby , Fana Gebreab , Melanie P Gygi , Hannah Parzen , John Szpyt , Stanley Tam , Gabriela Zarraga , Laura Pontano-Vaites , Sharan Swarup , Anne E White , Devin K Schweppe , Ramin Rad , Brian K Erickson , Robert A Obar , K G Guruharsha , Kejie Li , Spyros Artavanis-Tsakonas , Steven P Gygi , J Wade Harper

High-Resolution CRISPR Screens Reveal Fitness Genes and Genotype-Specific Cancer Liabilities.

Cell     Traver Hart , Megha Chandrashekhar , Michael Aregger , Zachary Steinhart , Kevin R Brown , Graham MacLeod , Monika Mis , Michal Zimmermann , Amelie Fradet-Turcotte , Song Sun , Patricia Mero , Peter Dirks , Sachdev Sidhu , Frederick P Roth , Olivia S Rissland , Daniel Durocher , Stephane Angers , Jason Moffat

A human interactome in three quantitative dimensions organized by stoichiometries and abundances.

Cell     Marco Y Hein , Nina C Hubner , Ina Poser , Jürgen Cox , Nagarjuna Nagaraj , Yusuke Toyoda , Igor A Gak , Ina Weisswange , Jörg Mansfeld , Frank Buchholz , Anthony A Hyman , Matthias Mann

The BioPlex Network: A Systematic Exploration of the Human Interactome.

Cell     Edward L Huttlin , Lily Ting , Raphael J Bruckner , Fana Gebreab , Melanie P Gygi , John Szpyt , Stanley Tam , Gabriela Zarraga , Greg Colby , Kurt Baltier , Rui Dong , Virginia Guarani , Laura Pontano Vaites , Alban Ordureau , Ramin Rad , Brian K Erickson , Martin Wühr , Joel Chick , Bo Zhai , Deepak Kolippakkam , Julian Mintseris , Robert A Obar , Tim Harris , Spyros Artavanis-Tsakonas , Mathew E Sowa , Pietro De Camilli , Joao A Paulo , J Wade Harper , Steven P Gygi

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

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Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.

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