| Type | Description |
|---|---|
| Definition | potassium two pore domain channel subfamily K member 18 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-20 13:35:00 | The Background K(+) Channel TRESK in Sensory Physiology and Pain. | 32717813 |
| 2020-05-23 10:34:00 | Nociceptors from migraine patients with the F139WfsX2 mutation show loss of functional TRESK at the membrane, with a corresponding significant increase in neuronal excitability. | 31742594 |
| 2019-12-14 11:05:00 | Results provide evidence that the activation of novel-type results in the slow (indirect) dephosphorylation of TRESK at the regulatory residue S264 in a calcineurin-independent manner. | 30992311 |
| 2019-08-03 12:52:00 | both human and rat TRESK contain potential anionic phospholipid binding sites (apbs) in the large cytoplasmic loop, but only the human channel is able to bind to multilamellar vesicles (MLVs), enriched with anionic phospholipids, suggesting an electrostatically mediated interaction. | 30039335 |
| 2016-12-17 11:18:00 | The presence of SCN1A mutations and absence of mutations in ATP1A2 or CACNA1A suggest that the Polish patients represent FHM type 3. | 26747084 |
| Type | IDs |
|---|---|
| Synonymous | K2p18.1, MGR13, TRESK, TRESK-2, TRESK2, TRIK |
| Gene |
UniProtKB-ID:
KCNKI_HUMAN
UniprotKB:
Q7Z418
UniParc:
UPI0000046427
EMBL:
AL731557,
AB087138
Ensembl:
ENSG00000186795
KO:
hsa:338567
|
| Nucleutide sequences |
EMBL-CDS:
BAC78527.1
Ensembl_TRS:
ENST00000334549
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000334650
RefSeq:
NP_862823.1
|
| Others |
UniRef100:
UniRef100_Q7Z418
UniRef90:
UniRef90_Q7Z418
UniRef50:
UniRef50_Q7Z418
UniGene:
Hs.449650
CCDS:
CCDS7598.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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